LncRNA:ENSG00000225783

Official Symbol

MIAT  provided by HGNC

Official Full Name

myocardial infarction associated transcript 

Gene ID

440823 

Chromosome

chr22

Start Site

26646411

End Site

26676475

Strand

Assembly

GRCh38

Biotype

lncRNA

Also known as

C22orf35|GOMAFU|LINC00066|NCRNA00066|RNCR2|lncRNA-MIAT 

Summary

This gene encodes a spliced long non-coding RNA that may constitute a component of the nuclear matrix. Altered expression of this locus has been reported to be associated with a susceptibility to myocardial infarction. It has also been proposed that pathways involving this transcript may contribute to the pathophysiology of schizophrenia. A similar gene in mouse has been associated with retinal cell fate determination. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Dec 2014] 

M6ARegulator:ENSG00000136231

Official Symbol

IGF2BP3  provided by HGNC

Official Full Name

insulin like growth factor 2 mRNA binding protein 3 

m6A Category

readers 

Gene ID

10643 

Chromosome

chr7 

Start Site

23310209 

End Site

23470491 

Strand

Assembly

GRCh38

Biotype

protein coding 

Also known as

CT98|IMP-3|IMP3|KOC|KOC1|VICKZ3 

Summary

"The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes. [provided by RefSeq, Jul 2008]" 

Differentially expressed Detail
Symbol MIAT  IGF2BP3 
Pvalue Not Available  Not Available 
Log2FC Not Available  Not Available 
Significant Not Available  Not Available 
Correlation coefficient 0.42 
Correlation FDR 1.0e-02