Official Symbol

FENDRR  provided by HGNC

Official Full Name

FOXF1 adjacent non-coding developmental regulatory RNA 

Gene ID

400550 

Chromosome

chr16

Start Site

86474529

End Site

86509099

Strand

- 

Assembly

GRCh38

Biotype

lncRNA

Also known as

FOXF1-AS1|FOXF1AS1|TCONS_00024240|lincFOXF1|onco-lncRNA-21 

Summary

This gene produces a spliced long non-coding RNA transcribed bidirectionally with FOXF1 on the opposite strand. A similar gene in mouse is essential for normal development of the heart and body wall. The encoded transcript is thought to act by binding to polycomb repressive complex 2 (PRC2) and/or TrxG/MLL complexes to promote the methylation of the promoters of target genes, thus reducing their expression. It has been suggested that this transcript may play a role in the progression of gastric cancer. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Mar 2015] 

Official Symbol

HNRNPC  provided by HGNC

Official Full Name

heterogeneous nuclear ribonucleoprotein C 

m6A Category

readers 

Gene ID

3183 

Chromosome

chr14 

Start Site

21209136 

End Site

21269494 

Strand

- 

Assembly

GRCh38

Biotype

protein coding 

Also known as

C1|C2|HNRNP|HNRPC|SNRPC 

Summary

"This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene can act as a tetramer and is involved in the assembly of 40S hnRNP particles. Multiple transcript variants encoding at least two different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]"