| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| SELP |
sodium;[(2S,3R,4R,5R,6R)-2,4,5-trihydroxy-6-[(2R,3S,4R)-2-(hydroxymethyl)-4-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl]oxyoxan-3-yl] hydrogen phosphate |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| SELP |
5-(2-{3,5-Dihydroxy-2-hydroxymethyl-6-[2-hydroxymethyl-4-(2,3,4-trihydroxy-5-methoxy-hexyloxy)-tetrahydro-pyran-3-yloxy]-tetrahydro-pyran-4-yloxy}-acetylamino)-2,4-dihydroxy-6-(1,2,3-trihydroxy-propyl)-tetrahydro-pyran-2-carboxylic acid |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| SELP |
5-Acetylamino-2-{3,5-dihydroxy-2-hydroxymethyl-6-[2-hydroxymethyl-4-(3,4,5-trihydroxy-6-methyl-tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-3-yloxy]-tetrahydro-pyran-4-yloxy}-4-hydroxy-6-((1R,2R)-1,2,3-trihydroxy-propyl)-tetrahydro-pyran-2-carboxylic acid |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| SELP |
sodium;[(2S,3R,4R,5R,6R)-2,4,5-trihydroxy-6-[(2R,3R,4R,5S)-5-hydroxy-2-(hydroxymethyl)-4-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl]oxyoxan-3-yl] sulfate |
NA |
670000 |
NA |
NA |
NA |
NA |
TTD |
| SELP |
sodium;[(2S,3R,4R,5R,6R)-2,4,5-trihydroxy-6-[(2R,3S,4R)-2-(hydroxymethyl)-4-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl]oxyoxan-3-yl] sulfate |
NA |
560000 |
NA |
NA |
NA |
NA |
TTD |
| SELP |
4-[((3R,5R)-1,3,4,5-Tetrahydroxy-cyclohexanecarbonyl)-amino]-butyric acid |
NA |
40000000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SELP |
6-[((R)-(R)-1,3,4,5-Tetrahydroxy-cyclohexanecarbonyl)-amino]-hexanoic acid |
NA |
50000000 |
NA |
NA |
NA |
NA |
TTD |
| SELP |
((3R,5R)-1,3,4,5-Tetrahydroxy-cyclohexanecarbonyl)-carbamic acid |
NA |
50000000 |
NA |
NA |
NA |
NA |
TTD |
| SELP |
(S)-2-[((3R,5R)-1,3,4,5-Tetrahydroxy-cyclohexanecarbonyl)-amino]-pentanedioic acid |
NA |
21000000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SELP |
[alpha-Neu5Ac-(2,3)-beta-D-Gal-(1,4) (alpha-Fuc-(1,3))-D-Glc] |
NA |
12000000 |
NA |
NA |
NA |
NA |
BindingDB |
| SELP |
(2S)-2-[[(3R,5R)-1,3,4,5-tetrahydroxycyclohexanecarbonyl]amino]propanoic acid |
NA |
50000000 |
NA |
NA |
NA |
NA |
TTD |
| SELP |
3-(2,2-difluoro-2-((2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)acetamido)benzoic acid |
NA |
2500000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SELP |
(S)-2-(2,2-difluoro-2-((2R,3S,4S,5S,6R)-2,3,4,5-tetrahydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)acetamido)pentanedioic acid |
NA |
11000000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SELP |
3-(2,2-difluoro-2-((2R,3S,4S,5S,6R)-2,3,4,5-tetrahydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)acetamido)benzoic acid |
NA |
6500000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SELP |
(S)-2-(2,2-difluoro-2-((2S,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)acetamido)pentanedioic acid |
NA |
3000000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SELP |
3-(2,2-difluoro-2-((2S,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)acetamido)benzoic acid |
NA |
5000000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SELP |
(S)-2-(2,2-difluoro-2-((2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)acetamido)pentanedioic acid |
NA |
11000000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SELP |
Sialyl Lewis X Antigen |
NA |
1300000|2000000|3400000|5000000|5500000|1000000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SELP |
(2R)-2-[(2S,3R,4S,5S,6R)-2-[(2R,3R)-1,4-dimethoxy-1,4-dioxo-3-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxybutan-2-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3-phenylpropanoic acid |
NA |
880000|4840000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SELP |
(2R)-2-[(2S,3R,4R,5S,6R)-2-[(2R,3R)-1,4-dimethoxy-1,4-dioxo-3-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxybutan-2-yl]oxy-3-hydroxy-6-(hydroxymethyl)-5-(naphthalene-1-carbonyloxy)oxan-4-yl]oxy-3-phenylpropanoic acid |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |