| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| USP7 |
US10766903, Example 93 |
NA |
100500 |
NA |
NA |
NA |
NA |
BindingDB |
| USP7 |
US10766903, Example 43 |
NA |
100500 |
NA |
NA |
NA |
NA |
BindingDB |
| USP7 |
US10766903, Example 39 |
NA |
100500 |
NA |
NA |
NA |
NA |
BindingDB |
| USP7 |
US10766903, Example 186 |
NA |
100500 |
NA |
NA |
NA |
NA |
BindingDB |
| USP7 |
US10766903, Example 192 |
NA |
100500 |
NA |
NA |
NA |
NA |
BindingDB |
| USP7 |
US10766903, Example 209 |
NA |
100500 |
NA |
NA |
NA |
NA |
BindingDB |
| USP7 |
6-[[4-Hydroxy-1-(3-phenylpropanoyl)piperidin-4-yl]methyl]-2-methylsulfanyl-[1,3]thiazolo[4,5-d]pyrimidin-7-one |
NA |
100500|130000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| USP7 |
3-[[4-Hydroxy-1-(3-phenylpropanoyl)piperidin-4-yl]methyl]furo[3,2-d]pyrimidin-4-one |
NA |
100500|115000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| USP7 |
US10766903, Example 112 |
NA |
100500 |
NA |
NA |
NA |
NA |
BindingDB |
| USP7 |
US10766903, Example 244 |
NA |
100500 |
NA |
NA |
NA |
NA |
BindingDB |
| USP7 |
US10766903, Example 132 |
NA |
100500 |
NA |
NA |
NA |
NA |
BindingDB |
| USP7 |
3-(2-Aminophenyl)-6-((4-hydroxy-1-((R)-3-phenylbutanoyl)piperidin-4-yl)methyl)-2-methyl-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one |
NA |
100500 |
NA |
NA |
NA |
NA |
BindingDB |
| USP7 |
US10766903, Example 126 |
NA |
100500 |
NA |
NA |
NA |
NA |
BindingDB |
| USP7 |
US10766903, Example 184 |
NA |
100500 |
NA |
NA |
NA |
NA |
BindingDB |
| USP7 |
US10766903, Example 198 |
NA |
100500 |
NA |
NA |
NA |
NA |
BindingDB |
| USP7 |
3-[[4-hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]pyrimidin-4-one |
NA |
100500 |
NA |
NA |
NA |
NA |
BindingDB |
| USP7 |
US10766903, Example 225 |
NA |
100500 |
NA |
NA |
NA |
NA |
BindingDB |
| USP7 |
(R)-3-((4-Hydroxy-1-(3-phenylbutanoyl)piperidin-4-yl)methyl)-6-(phenylethynyl)pyrimidin-4(3H)-one |
NA |
100500 |
NA |
NA |
NA |
NA |
BindingDB |
| USP7 |
3-[[4-Hydroxy-1-(3-phenylpropanoyl)piperidin-4-yl]methyl]furo[2,3-d]pyrimidin-4-one |
NA |
100500 |
NA |
NA |
NA |
NA |
BindingDB |
| USP7 |
US10766903, Example 156 |
NA |
100500 |
NA |
NA |
NA |
NA |
BindingDB |