| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| F10 |
((R)-2-{(S)-2-[(6-Amino-2,4-dimethyl-pyridin-3-ylmethyl)-carbamoyl]-pyrrolidin-1-yl}-1-benzhydryl-2-oxo-ethyl)-carbamic acid tert-butyl ester |
160000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| F10 |
(2S)-1-[(2R)-2-(benzylsulfonylamino)-3-(3,4-dichlorophenyl)propanoyl]-N-(pyridin-4-ylmethyl)pyrrolidine-2-carboxamide |
200000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| F10 |
(S)-1-(2-5H-Dibenzo[a,d]cyclohepten-5-yl-acetyl)-pyrrolidine-2-carboxylic acid (4-amino-cyclohexylmethyl)-amide; hydrochloride |
1000000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| F10 |
(2S)-1-[(2R)-2-(benzylsulfonylamino)-3-(3,4-dichlorophenyl)propanoyl]-N-(pyridin-3-ylmethyl)pyrrolidine-2-carboxamide |
230000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| F10 |
(S)-1-(3,3-Dicyclohexyl-propionyl)-pyrrolidine-2-carboxylic acid (4-amino-cyclohexylmethyl)-amide; hydrochloride |
220000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| F10 |
(2S)-1-[(2R)-2-amino-3,3-dicyclohexylpropanoyl]-N-[(6-amino-2,4-dimethylpyridin-3-yl)methyl]pyrrolidine-2-carboxamide |
160000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| F10 |
((R)-2-{(S)-2-[(6-Amino-pyridin-3-ylmethyl)-carbamoyl]-pyrrolidin-1-yl}-1-benzhydryl-2-oxo-ethyl)-carbamic acid tert-butyl ester |
200000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| F10 |
benzyl N-(4-amino-1-diphenoxyphosphorylbutyl)carbamate |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| F10 |
2-Phenyl-1H-benzoimidazole-5-carboxamidine |
125000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| F10 |
N-((R)-2-Amino-4,5,6,7-tetrahydro-benzothiazol-6-yl)-2-(6-methyl-2-oxo-3-phenylmethanesulfonylamino-2H-pyridin-1-yl)-acetamide |
225200 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| F10 |
(S)-3-{[2-(4-Carbamimidoyl-benzyloxy)-4-methyl-3-oxo-3,4-dihydro-2H-benzo[1,4]oxazine-7-carbonyl]-amino}-3-phenyl-propionic acid |
200000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| F10 |
3-Amidinophenylalanine deriv., 29 |
1000000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| F10 |
2-[3-(4-Fluoro-phenylmethanesulfonylamino)-6-methyl-2-oxo-2H-pyridin-1-yl]-N-(4,5,6,7-tetrahydro-2H-indazol-5-ylmethyl)-acetamide |
314000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| F10 |
3-Amidinophenylalanine deriv., 27 |
130000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| F10 |
{(R)-2-[(S)-2-(4-Amino-benzylcarbamoyl)-pyrrolidin-1-yl]-1-benzyl-2-oxo-ethyl}-carbamic acid tert-butyl ester |
420000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| F10 |
Sodium;[2-[[6-methoxy-3-[(2-methylpropan-2-yl)oxycarbonyl]-1-benzofuran-5-yl]oxymethyl]-1,3-benzothiazol-6-yl] sulfate |
NA |
352000 |
NA |
NA |
NA |
NA |
TTD |
| F10 |
sodium;[2-[(2-benzyl-3-ethoxycarbonyl-6-methoxy-1-benzofuran-5-yl)oxymethyl]-3-ethoxycarbonyl-1H-indol-5-yl] sulfate |
NA |
195000 |
NA |
NA |
NA |
NA |
TTD |
| F10 |
sodium;[3-ethoxycarbonyl-2-[(3-ethoxycarbonyl-2-methyl-1H-indol-5-yl)oxymethyl]-1-[(2-methylpropan-2-yl)oxycarbonyl]indol-5-yl] sulfate |
NA |
229000 |
NA |
NA |
NA |
NA |
TTD |
| F10 |
sodium;[3-ethoxycarbonyl-2-[[3-ethoxycarbonyl-2-[(3-ethoxycarbonyl-6-methoxy-2-methyl-1-benzofuran-5-yl)oxymethyl]-6-methoxy-1-benzofuran-5-yl]oxymethyl]-1H-indol-5-yl] sulfate |
NA |
344000 |
NA |
NA |
NA |
NA |
TTD |
| F10 |
[2-[[6-Methoxy-3-[(2-methylpropan-2-yl)oxycarbonyl]-1-benzofuran-5-yl]oxymethyl]-1,3-benzothiazol-6-yl] sulfate |
NA |
352000 |
NA |
NA |
NA |
NA |
BindingDB |