| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| ACHE |
(2E)-1-[6-[(1-benzylpiperidin-4-yl)methoxy]pyridin-2-yl]-2-hydroxyiminoethanone |
199100 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
9-(5-Pyridin-2-ylpentylsulfanyl)-1,2,3,4-tetrahydroacridine |
NA |
130000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
|
NA |
307000 |
NA |
NA |
NA |
NA |
BindingDB |
| ACHE |
(2E)-1-[6-[[1-[(3,4-difluorophenyl)methyl]piperidin-4-yl]methoxy]pyridin-3-yl]-2-hydroxyiminoethanone |
158800 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
4-[[4-[[5-[(2E)-2-hydroxyiminoacetyl]pyridin-2-yl]oxymethyl]piperidin-1-yl]methyl]benzonitrile |
1608000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
(2E)-1-[6-[[1-[(3-chlorophenyl)methyl]piperidin-4-yl]methoxy]pyridin-3-yl]-2-hydroxyiminoethanone |
298300 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
(2E)-1-[6-[(1-benzylpiperidin-2-yl)methoxy]pyridin-3-yl]-2-hydroxyiminoethanone |
550600 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
(2Z)-2-hydroxyimino-N-[1-[6-[3-[[(2Z)-2-hydroxyiminoacetyl]amino]pyridin-1-ium-1-yl]hexyl]pyridin-1-ium-3-yl]acetamide;dibromide |
NA |
1430000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
(2Z)-2-hydroxyimino-N-[1-[7-[3-[[(2Z)-2-hydroxyiminoacetyl]amino]pyridin-1-ium-1-yl]heptyl]pyridin-1-ium-3-yl]acetamide;dibromide |
NA |
930000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
(2E)-2-hydroxyimino-N-[1-[[3-[[3-[[(2E)-2-hydroxyiminoacetyl]amino]pyridin-1-ium-1-yl]methyl]phenyl]methyl]pyridin-1-ium-3-yl]acetamide;dibromide |
NA |
1670000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
(2Z)-2-hydroxyimino-N-[1-[3-[3-[[(2Z)-2-hydroxyiminoacetyl]amino]pyridin-1-ium-1-yl]propyl]pyridin-1-ium-3-yl]acetamide;dibromide |
NA |
1070000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
(2Z)-2-hydroxyimino-N-[1-[4-[3-[[(2Z)-2-hydroxyiminoacetyl]amino]pyridin-1-ium-1-yl]butyl]pyridin-1-ium-3-yl]acetamide;dibromide |
NA |
1060000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
(2Z)-2-hydroxyimino-N-[1-[5-[3-[[(2Z)-2-hydroxyiminoacetyl]amino]pyridin-1-ium-1-yl]pentyl]pyridin-1-ium-3-yl]acetamide;dibromide |
NA |
1790000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
|
NA |
189000 |
NA |
NA |
NA |
NA |
BindingDB |
| ACHE |
2-(dimethylamino)ethyl N-(2-chloropyridin-4-yl)carbamate;trihydrochloride |
207700 |
NA |
NA |
NA |
NA |
NA |
TTD |
| ACHE |
2-(dimethylamino)ethyl N-(3-bromopyridin-4-yl)carbamate;dihydrochloride |
316400 |
NA |
NA |
NA |
NA |
NA |
TTD |
| ACHE |
trimethyl-[2-[(1R,4S,5R,9S,10R,13S)-5,9,13-trimethyl-14-oxotetracyclo[11.2.1.01,10.04,9]hexadecane-5-carbonyl]oxyethyl]azanium;iodide |
NA |
150000 |
NA |
NA |
NA |
NA |
TTD |
| ACHE |
4-Carbamoyl-1-(3-(4-((hydroxyimino)methyl)pyridinium-1-yl)propyl)pyridinium bromide |
NA |
711000 |
NA |
NA |
NA |
NA |
BindingDB |
| ACHE |
4-[6-(6,7-dimethoxy-1-phenyl-3,4-dihydro-1H-isoquinolin-2-yl)hexyl]-6-methyl-2-(nitrosomethyl)pyridin-3-ol |
NA |
300000 |
NA |
NA |
NA |
NA |
BindingDB |
| ACHE |
4-[5-(6,7-dimethoxy-1-phenyl-3,4-dihydro-1H-isoquinolin-2-yl)pentyl]-2-(nitrosomethyl)pyridin-3-ol |
NA |
320000 |
NA |
NA |
NA |
NA |
BindingDB |