| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| USP7 |
4-[6-Amino-5-(4-hydroxyphenyl)-4-isopropyl-3-pyridyl]phenol |
NA |
197000 |
NA |
NA |
NA |
NA |
BindingDB |
| USP7 |
(R)-3-(4-(Aminomethyl)phenyl)-6-((4-hydroxy-1-(3-phenylbutanoyl)piperidin-4-yl)methyl)-2-methyl-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one |
NA |
NA |
471000 |
NA |
NA |
NA |
BindingDB |
| USP7 |
Usp7-IN-4 |
NA |
NA |
471000 |
NA |
NA |
NA |
BindingDB |
| USP7 |
US10766903, Example 96 |
NA |
100500 |
NA |
NA |
NA |
NA |
BindingDB |
| USP7 |
US10766903, Example 18 |
NA |
100500 |
NA |
NA |
NA |
NA |
BindingDB |
| USP7 |
US10766903, Example 1 |
NA |
100500 |
NA |
NA |
NA |
NA |
BindingDB |
| USP7 |
US10766903, Example 45 |
NA |
100500 |
NA |
NA |
NA |
NA |
BindingDB |
| USP7 |
(R)-3-((4-Hydroxy-1-(3-phenylbutanoyl)piperidin-4-yl)methyl)-6-(phenylamino)pyrimidin-4(3H)-one |
NA |
100500 |
NA |
NA |
NA |
NA |
BindingDB |
| USP7 |
US10766903, Example 81 |
NA |
100500 |
NA |
NA |
NA |
NA |
BindingDB |
| USP7 |
US10766903, Example 14 |
NA |
100500 |
NA |
NA |
NA |
NA |
BindingDB |
| USP7 |
US10766903, Example 115 |
NA |
100500 |
NA |
NA |
NA |
NA |
BindingDB |
| USP7 |
US10766903, Example 111 |
NA |
100500 |
NA |
NA |
NA |
NA |
BindingDB |
| USP7 |
US10766903, Example 16 |
NA |
100500 |
NA |
NA |
NA |
NA |
BindingDB |
| USP7 |
(R)-6-(2-(Dimethylamino)ethoxy)-3-((4-hydroxy-1-(3-phenylbutanoyl)piperidin-4-yl)methyl)pyrimidin-4(3H)-one |
NA |
100500 |
NA |
NA |
NA |
NA |
BindingDB |
| USP7 |
US10766903, Example 20 |
NA |
100500 |
NA |
NA |
NA |
NA |
BindingDB |
| USP7 |
US10766903, Example 19 |
NA |
100500 |
NA |
NA |
NA |
NA |
BindingDB |
| USP7 |
(R)-6-((4-Hydroxy-1-(3-phenylbutanoyl)piperidin-4-yl)methyl)-3-(3-hydroxy-3-methylbut-1-yn-1-yl)-2-methyl-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one |
NA |
100500 |
NA |
NA |
NA |
NA |
BindingDB |
| USP7 |
6-[[4-Hydroxy-1-(3-phenylpropanoyl)piperidin-4-yl]methyl]-2-methylpyrazolo[4,3-d]pyrimidin-7-one |
NA |
100500 |
NA |
NA |
NA |
NA |
BindingDB |
| USP7 |
US10766903, Example 34 |
NA |
100500 |
NA |
NA |
NA |
NA |
BindingDB |
| USP7 |
US10766903, Example 44 |
NA |
100500 |
NA |
NA |
NA |
NA |
BindingDB |