| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| YES1 |
[5-{2-[1-(3-Carbamoyl-4-cyclohexylmethoxy-phenyl)-1-methyl-ethylcarbamoyl]-ethyl}-2-(tetrazol-1-ylmethoxy)-phenyl]-phosphonic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| YES1 |
(4-{2-Acetylamino-2-[(S)-1-(3-carbamoyl-4-cyclohexylmethoxy-phenyl)-ethylcarbamoyl]-ethyl}-phenoxy)-acetic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| YES1 |
{4-[2-Acetylamino-2-(3-carbamoyl-4-cyclohexylmethoxy-phenylcarbamoyl)-ethyl]-2-phosphono-phenoxy}-acetic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| YES1 |
(4-{2-[1-(3-Carbamoyl-4-cyclohexylmethoxy-phenyl)-1-methyl-ethylcarbamoyl]-ethyl}-2-phosphono-phenoxy)-acetic acid |
NA |
303000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| YES1 |
(5-{2-[1-(3-Carbamoyl-4-cyclohexylmethoxy-phenyl)-1-methyl-ethylcarbamoyl]-ethyl}-2-hydroxy-phenyl)-phosphonic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| YTHDF2 |
6-Cyclopropyl-1,2,3,4-tetrahydropyrimidine-2,4-dione |
NA |
410000|174000 |
NA |
NA |
NA |
NA |
BindingDB|ChEMBL |
| YTHDF2 |
N-methyl-3-phenyl-1H-pyrazolo[4,3-d]pyrimidin-7-amine |
NA |
491000|161000 |
NA |
NA |
NA |
NA |
BindingDB|ChEMBL |
| YTHDF2 |
6-Cyclopropyl-3-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione |
NA |
161000|491000 |
NA |
NA |
NA |
NA |
BindingDB|ChEMBL |
| YTHDF2 |
N,3-Dimethyl-1H-pyrazolo[4,3-D]pyrimidin-7-amine |
NA |
174000|410000 |
NA |
NA |
NA |
NA |
BindingDB|ChEMBL |
| YWHAH |
Trisenox |
NA |
NA |
110000 |
NA |
NA |
NA |
PubChem |
| ZAP70 |
[4-{2-Acetylamino-2-[(S)-1-(3-carbamoyl-4-cyclohexylmethoxy-phenyl)-ethylcarbamoyl]-ethyl}-2-(ethoxy-hydroxy-phosphoryl)-phenoxy]-acetic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| ZAP70 |
(4-{2-Acetylamino-2-[(S)-1-(3-carbamoyl-4-cyclohexylmethoxy-phenyl)-ethylcarbamoyl]-ethyl}-2-phosphono-phenoxy)-acetic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| ZAP70 |
[4-[3-[[(1S)-1-[3-[(3,4-dichlorophenyl)methyl]-1,2,4-oxadiazol-5-yl]ethyl]amino]-3-oxopropyl]phenyl] dihydrogen phosphate |
NA |
198000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ZAP70 |
Trifluoro-methanesulfonic acid 4-{2-[1-(3-carbamoyl-4-cyclohexylmethoxy-phenyl)-1-methyl-ethylcarbamoyl]-ethyl}-2-phosphono-phenyl ester |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| ZAP70 |
{4-[2-Acetylamino-2-(3-carbamoyl-4-cyclohexylmethoxy-benzylcarbamoyl)-ethyl]-2-phosphono-phenoxy}-acetic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| ZAP70 |
(4-{2-Acetylamino-2-[1-(3-carbamoyl-4-cyclohexylmethoxy-phenyl)-1-methyl-ethylcarbamoyl]-ethyl}-2-phosphono-phenoxy)-acetic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| ZAP70 |
[5-{2-[1-(3-Carbamoyl-4-cyclohexylmethoxy-phenyl)-1-methyl-ethylcarbamoyl]-ethyl}-2-(tetrazol-1-ylmethoxy)-phenyl]-phosphonic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| ZAP70 |
[4-[2-acetamido-3-[[(1S)-1-[3-carbamoyl-4-(cyclohexylmethoxy)phenyl]ethyl]amino]-3-oxopropyl]phenyl] dihydrogen phosphate |
NA |
441000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ZAP70 |
{4-[2-Acetylamino-2-(3-carbamoyl-4-cyclohexylmethoxy-phenylcarbamoyl)-ethyl]-2-phosphono-phenoxy}-acetic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| ZAP70 |
(4-{2-[1-(3-Carbamoyl-4-cyclohexylmethoxy-phenyl)-1-methyl-ethylcarbamoyl]-ethyl}-2-phosphono-phenoxy)-acetic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |