| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| ADK |
2-(4-Amino-5-iodo-pyrrolo[2,3-d]pyrimidin-7-yl)-5-ethyl-tetrahydro-furan-3,4-diol |
NA |
60006735 |
NA |
NA |
NA |
NA |
BindingDB |
| ADK |
2-(4-Amino-5-bromo-pyrrolo[2,3-d]pyrimidin-7-yl)-5-methyl-tetrahydro-furan-3,4-diol |
NA |
40003685 |
NA |
NA |
NA |
NA |
BindingDB |
| ADK |
2-(4-Amino-5-bromo-pyrrolo[2,3-d]pyrimidin-7-yl)-5-azidomethyl-tetrahydro-furan-3,4-diol |
NA |
62994118 |
NA |
NA |
NA |
NA |
BindingDB |
| ADK |
2-(4-Chloro-5-methylsulfanyl-pyrrolo[2,3-d]pyrimidin-7-yl)-5-methyl-tetrahydro-furan-3,4-diol |
NA |
70000316 |
NA |
NA |
NA |
NA |
BindingDB |
| ADK |
2-Azidomethyl-5-(4-chloro-5-iodo-pyrrolo[2,3-d]pyrimidin-7-yl)-tetrahydro-furan-3,4-diol |
NA |
8999119 |
NA |
NA |
NA |
NA |
BindingDB |
| ADK |
2-(4-Amino-5-methylsulfanyl-pyrrolo[2,3-d]pyrimidin-7-yl)-5-methyl-tetrahydro-furan-3,4-diol |
NA |
1349895035 |
NA |
NA |
NA |
NA |
BindingDB |
| ADK |
2-(4-Amino-5-methyl-pyrrolo[2,3-d]pyrimidin-7-yl)-5-methyl-tetrahydro-furan-3,4-diol |
NA |
60603820 |
NA |
NA |
NA |
NA |
BindingDB |
| ADK |
2-(4-Amino-5-iodo-pyrrolo[2,3-d]pyrimidin-7-yl)-5-azidomethyl-tetrahydro-furan-3,4-diol |
NA |
35002575 |
NA |
NA |
NA |
NA |
BindingDB |
| ADK |
4-Amino-7-(3,4-dihydroxy-5-methyl-tetrahydro-furan-2-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carboxylic acid ethyl ester |
NA |
1000000000 |
NA |
NA |
NA |
NA |
BindingDB |
| ADK |
5'-Deoxytoyocamycin |
NA |
310027344 |
NA |
NA |
NA |
NA |
BindingDB |
| ADK |
Sangivamycin |
NA |
470002318 |
NA |
NA |
NA |
NA |
BindingDB |
| ADK |
4-Chloro-5-iodo-7-(beta-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine |
NA |
23999379 |
NA |
NA |
NA |
NA |
BindingDB |
| ADK |
6-Phenylpyrrolo[2,1-d][1,5]benzothiazepin-7-one |
NA |
130000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ADK |
6-Ethyl-6-(m-tolyl)pyrrolo[2,1-d][1,5]benzoxazepin-7-one |
NA |
150000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ADK |
4-Amino-7-(3,4-dihydroxy-5-methyl-tetrahydro-furan-2-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carboxylic acid amide |
NA |
460044666 |
NA |
NA |
NA |
NA |
BindingDB |
| ADK |
7-[(3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]-5-iodo-1H-pyrrolo[2,3-d]pyrimidine-4-thione |
NA |
154881661.9 |
NA |
NA |
NA |
NA |
TTD |
| ADK |
ethyl 4-amino-7-[(3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]pyrrolo[2,3-d]pyrimidine-5-carboxylate |
NA |
1000000000 |
NA |
NA |
NA |
NA |
TTD |
| ADK |
(3R,4S,5R)-2-(4-amino-5-methylsulfanylpyrrolo[2,3-d]pyrimidin-7-yl)-5-methyloxolane-3,4-diol |
NA |
741310241.3 |
NA |
NA |
NA |
NA |
TTD |
| ADK |
(3R,4S,5R)-2-(4-amino-5-methylpyrrolo[2,3-d]pyrimidin-7-yl)-5-methyloxolane-3,4-diol |
NA |
60255958.61 |
NA |
NA |
NA |
NA |
TTD |
| ADK |
6-[4-[[3-[2-(Diethylamino)ethyl]phenoxy]methyl]phenyl]-6-ethylpyrrolo[2,1-d][1,5]benzoxazepin-7-one |
NA |
200000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |