| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| ADORA1 |
11-Methyl-4-(4-nitrophenyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine |
300000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| ADORA1 |
Theobromine |
NA|105000 |
105000|NA |
NA |
NA |
NA |
NA |
BindingDB|PubChem |
| ADORA1 |
Cefepime |
NA |
NA |
NA |
NA |
NA |
300000 |
PubChem |
| ADORA1 |
Ceftazidime |
NA |
NA |
NA |
NA |
NA |
300000 |
PubChem |
| ADORA1 |
5-Phenyl-1,2,4-thiadiazol-3-amine |
NA |
NA |
122000 |
NA |
NA |
NA |
BindingDB|ChEMBL |
| ADORA1 |
(2S,3S,4R,5R)-5-[2-[2-[4-[(3,5-ditert-butyl-4-hydroxybenzoyl)amino]phenyl]ethylamino]-6-(2,2-diphenylethylamino)purin-9-yl]-3,4-dihydroxy-N-methyloxolane-2-carboxamide |
NA |
413267 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ADORA1 |
Aztreonam |
NA |
NA |
NA |
NA |
NA |
400000 |
PubChem |
| ADORA1 |
Carumonam |
NA |
NA |
NA |
NA |
NA |
500000 |
PubChem |
| ADORA1 |
Doripenem |
NA |
NA |
NA |
NA |
NA |
300000 |
PubChem |
| ADORA1 |
(2-amino-4H-indeno[1,2-d][1,3]thiazol-5-yl) acetate;hydroiodide |
NA |
NA |
NA |
501187234|501187233.6 |
NA |
NA |
BindingDB|TTD |
| ADORA2A |
3-(2,6-Dioxo-3-propyl-2,3,6,7-tetrahydro-purin-1-yl)-propionitrile |
162000 |
NA |
NA |
NA |
NA |
NA |
BindingDB |
| ADORA2A |
2-Cyclohexyl-4,6-dimethyl-2,4-dihydro-[1,2,3]triazolo[4,5-d]pyrimidine-5,7-dione |
250000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ADORA2A |
1-(3-Oxo-butyl)-3-propyl-3,7-dihydro-purine-2,6-dione |
144000 |
NA |
NA |
NA |
NA |
NA |
BindingDB |
| ADORA2A |
1-Cyclopentyl-4,6-dimethyl-1,4-dihydro-[1,2,3]triazolo[4,5-d]pyrimidine-5,7-dione |
292000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ADORA2A |
Imipenem |
NA |
NA |
NA |
NA |
NA |
300000 |
PubChem |
| ADORA2A |
(10aS)-2-(2-pyridin-2-ylethyl)-1,5,10,10a-tetrahydroimidazo[1,5-b]isoquinolin-3-imine;dihydrochloride |
200000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| ADORA2A |
(10aS)-2-(2-morpholin-4-ylethyl)-1,5,10,10a-tetrahydroimidazo[1,5-b]isoquinolin-3-imine;dihydrochloride |
200000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| ADORA2A |
(4S)-1,4-dibenzyl-4,5-dihydroimidazol-2-amine;hydrochloride |
200000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| ADORA2A |
1,4-Dibenzyl-3-methylimidazolidin-2-imine;hydrochloride |
200000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| ADORA2A |
(4S)-1-benzyl-4-[(4-fluorophenyl)methyl]-4,5-dihydroimidazol-2-amine;hydrochloride |
200000 |
NA |
NA |
NA |
NA |
NA |
TTD |