| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| ADRB3 |
N-{4-[2-((R)-2-Hydroxy-2-pyridin-3-yl-ethylamino)-ethyl]-phenyl}-4-(4-octyl-3,5-dioxo-[1,2,4]triazolidin-1-yl)-benzenesulfonamide |
NA |
NA |
NA |
9990000|10000000 |
NA |
NA |
BindingDB |
| ADRB3 |
4-(1-Hexyl-5-oxo-1,5-dihydro-[1,2,4]triazol-4-yl)-N-{4-[2-(2-hydroxy-2-pyridin-3-yl-ethylamino)-ethyl]-phenyl}-benzenesulfonamide |
NA |
NA |
NA |
10000000 |
NA |
NA |
BindingDB |
| ADRB3 |
4-(4-Hexyl-5-oxo-4,5-dihydro-[1,2,4]triazol-1-yl)-N-{4-[2-(2-hydroxy-2-pyridin-3-yl-ethylamino)-ethyl]-phenyl}-benzenesulfonamide |
NA |
NA |
NA |
165958691 |
NA |
NA |
BindingDB |
| ADRB3 |
N-{4-[2-(2-Hydroxy-2-pyridin-3-yl-ethylamino)-ethyl]-phenyl}-4-[2-oxo-3-(3-oxo-3-pyrrolidin-1-yl-propyl)-imidazolidin-1-yl]-benzenesulfonamide |
NA |
NA |
NA |
7762471 |
NA |
NA |
BindingDB |
| ADRB3 |
N-{4-[2-((R)-2-Hydroxy-2-pyridin-3-yl-ethylamino)-ethyl]-phenyl}-4-[2-oxo-3-(4,4,4-trifluoro-butyl)-imidazolidin-1-yl]-benzenesulfonamide |
NA |
NA |
NA |
54954087 |
NA |
NA |
BindingDB |
| ADRB3 |
N-{4-[2-(2-Hydroxy-2-pyridin-3-yl-ethylamino)-ethyl]-phenyl}-4-(1-octyl-5-oxo-[1,2,4]triazolidin-4-yl)-benzenesulfonamide |
NA |
NA |
NA |
66069345 |
NA |
NA |
BindingDB |
| ADRB3 |
N-{4-[2-(2-Hydroxy-2-pyridin-3-yl-ethylamino)-ethyl]-phenyl}-4-(4-octyl-5-oxo-[1,2,4]triazolidin-1-yl)-benzenesulfonamide |
NA |
NA |
NA |
186208714 |
NA |
NA |
BindingDB |
| ADRB3 |
N-{4-[2-((R)-2-Hydroxy-2-pyridin-3-yl-ethylamino)-ethyl]-phenyl}-4-(4-methyl-3-octyl-2-oxo-2,3-dihydro-imidazol-1-yl)-benzenesulfonamide |
NA |
NA |
NA |
16595869 |
NA |
NA |
BindingDB |
| ADRB3 |
4-(3-Hexyl-4-methyl-2-oxo-2,3-dihydro-imidazol-1-yl)-N-{4-[2-((R)-2-hydroxy-2-pyridin-3-yl-ethylamino)-ethyl]-phenyl}-benzenesulfonamide |
NA |
NA |
NA |
12302688 |
NA |
NA |
BindingDB |
| ADRB3 |
N-{4-[2-((R)-2-Hydroxy-2-pyridin-3-yl-ethylamino)-ethyl]-phenyl}-4-(3-octyl-2-oxo-2,3-dihydro-imidazol-1-yl)-benzenesulfonamide |
NA |
NA |
NA |
295120923 |
NA |
NA |
BindingDB |
| ADRB3 |
N-{4-[2-((R)-2-Hydroxy-2-pyridin-3-yl-ethylamino)-ethyl]-phenyl}-4-[2-oxo-3-(4,4,5,5,5-pentafluoro-pentyl)-imidazolidin-1-yl]-benzenesulfonamide |
NA |
NA |
NA |
70794578 |
NA |
NA |
BindingDB |
| ADRB3 |
N-[4-[2-[[(2S)-2-hydroxy-3-phenoxypropyl]amino]ethyl]phenyl]benzamide |
NA |
NA |
NA |
130000 |
NA |
NA |
BindingDB |
| ADRB3 |
4-(3-Hexyl-2,4-dioxo-imidazolidin-1-yl)-N-{4-[2-(2-hydroxy-2-pyridin-3-yl-ethylamino)-ethyl]-phenyl}-benzenesulfonamide |
NA |
NA |
NA |
77624712 |
NA |
NA |
BindingDB |
| ADRB3 |
Terbutaline |
NA |
NA |
125893 |
NA |
NA |
NA |
BindingDB |
| ADRB3 |
N-{4-[2-(2-Hydroxy-2-pyridin-3-yl-ethylamino)-ethyl]-phenyl}-4-(3-octyl-2,4-dioxo-imidazolidin-1-yl)-benzenesulfonamide |
NA |
NA |
NA |
204173794 |
NA |
NA |
BindingDB |
| ADRB3 |
N-{4-[2-(2-Hydroxy-2-pyridin-3-yl-ethylamino)-ethyl]-phenyl}-4-(3-octyl-2,5-dioxo-imidazolidin-1-yl)-benzenesulfonamide |
NA |
NA |
NA |
63095734 |
NA |
NA |
BindingDB |
| ADRB3 |
4-(3-Hexyl-2,5-dioxo-imidazolidin-1-yl)-N-{4-[2-(2-hydroxy-2-pyridin-3-yl-ethylamino)-ethyl]-phenyl}-benzenesulfonamide |
NA |
NA |
NA |
3630781 |
NA |
NA |
BindingDB |
| AGA |
Methylsuccinic acid |
700000 |
NA |
NA |
NA |
NA |
NA |
BindingDB |
| AGA |
Succinic Acid |
5000000 |
NA |
NA |
NA |
NA |
NA |
BindingDB |
| AGA |
N-[3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]-2-aminoacetamide |
750000 |
NA |
NA |
NA |
NA |
NA |
BindingDB |