| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| SCN5A |
6-((((1R,4r)-4-((R)-1-Amino-2-(7-methoxy-2-oxo-1,5-naphthyridin-1(2H)-yl)ethyl)cyclohexyl)amino)methyl)-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one |
NA |
333000 |
NA |
NA |
NA |
NA |
TTD |
| SCN5A |
2-[[[4-[(1R)-1-amino-2-(7-fluoro-2-oxoquinoxalin-1-yl)ethyl]cyclohexyl]amino]methyl]-8H-pyrimido[5,4-b][1,4]oxazin-7-one |
NA |
333000 |
NA |
NA |
NA |
NA |
TTD |
| SCN5A |
Risperidone |
NA |
102000 |
NA |
NA |
NA |
NA |
PubChem|TTD |
| SCN5A |
Raltegravir |
NA |
316228|1584890|316227.77 |
NA |
NA |
NA |
NA |
PubChem|TTD |
| SCN5A |
Alvimopan |
NA |
251189|251188.64 |
NA |
NA |
NA |
NA |
PubChem|TTD |
| SCN5A |
6-[4-(4-Fluorophenoxy)phenyl]-2-[(5-methyl-1,2,4-oxadiazol-3-yl)methyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one |
NA |
541000 |
NA |
NA |
NA |
NA |
TTD |
| SCN5A |
6-[4-(4-Chlorophenoxy)phenyl]-2-[(3-methyl-1,2,4-oxadiazol-5-yl)methyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one |
NA |
134000 |
NA |
NA |
NA |
NA |
TTD |
| SCN5A |
6-[4-(4-Fluorophenoxy)phenyl]-2-[(3-methyl-1,2,4-oxadiazol-5-yl)methyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one |
NA |
215000 |
NA |
NA |
NA |
NA |
TTD |
| SCN5A |
Ranolazine |
NA |
428000 |
NA |
NA |
NA |
NA |
PubChem |
| SCN5A |
2-[(5-Cyclopropyl-1,3,4-oxadiazol-2-yl)methyl]-6-[4-(4-fluorophenoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one |
NA |
740000 |
NA |
NA |
NA |
NA |
TTD |
| SCN5A |
6-[4-(4-fluorophenoxy)phenyl]-2H-[1,2,4]triazolo[4,3-a]pyridin-3-one |
NA |
1903000 |
NA |
NA |
NA |
NA |
TTD |
| SCN5A |
6-[4-(4-Fluorophenoxy)phenyl]-2-[[5-(hydroxymethyl)-1,2,4-oxadiazol-3-yl]methyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one |
NA |
981000 |
NA |
NA |
NA |
NA |
TTD |
| SCN5A |
Nelfinavir |
NA |
501187|501187.23 |
NA |
NA |
NA |
NA |
PubChem|TTD |
| SCN5A |
Everolimus |
NA |
630957|199526|199526.23 |
NA |
NA |
NA |
NA |
PubChem|TTD |
| SCN5A |
Nilotinib |
NA |
1000000|5011870 |
NA |
NA |
NA |
NA |
PubChem|TTD |
| SCN5A |
Ambrisentan |
NA |
1258930|1000000 |
NA |
NA |
NA |
NA |
PubChem|TTD |
| SCN5A |
Dofetilide |
NA |
300000|630957|316228 |
NA |
NA |
NA |
NA |
PubChem|TTD |
| SCN5A |
Doripenem |
NA |
1584890|1584893.19 |
NA |
NA |
NA |
NA |
PubChem|TTD |
| SCN5A |
4-[[(2R)-2-hydroxy-2-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl]amino]butyl 5-[[3-[(S)-[[(3R)-1-azabicyclo[2.2.2]octan-3-yl]oxycarbonylamino]-phenylmethyl]phenoxy]methyl]-1-methylpyrazole-3-carboxylate |
NA |
121000 |
NA |
NA |
NA |
NA |
PubChem |
| SCN7A |
Dofetilide |
NA |
300000 |
NA |
NA |
NA |
NA |
PubChem |