| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| SCN3A |
Lidocaine |
NA |
240000 |
NA |
NA |
NA |
NA |
PubChem |
| SCN3A |
Metoprolol |
NA |
117000 |
NA |
NA |
NA |
NA |
PubChem |
| SCN3A |
Procaine |
NA |
110000 |
NA |
NA |
NA |
NA |
PubChem |
| SCN3A |
(1R,3R,8S,9R,12S,13R,14S)-1-hydroxy-14-(2-hydroxypropan-2-yl)-13-methyl-4,7,10-trioxapentacyclo[6.4.1.19,12.03,5.05,13]tetradecane-6,11-dione;(1R,3R,8S,9R,12S,13R,14R)-1-hydroxy-13-methyl-14-prop-1-en-2-yl-4,7,10-trioxapentacyclo[6.4.1.19,12.03,5.05,13]tetradecane-6,11-dione |
NA |
700000 |
NA |
NA |
NA |
NA |
PubChem |
| SCN3A |
Dofetilide |
NA |
300000 |
NA |
NA |
NA |
NA |
PubChem |
| SCN4A |
(2R)-N-(2,6-dimethylphenyl)-N,1-dimethylpyrrolidine-2-carboxamide |
NA |
NA |
NA |
501187.23 |
NA |
NA |
TTD |
| SCN4A |
(2S)-N-(2,6-dimethylphenyl)-N,1-dimethylpyrrolidine-2-carboxamide |
NA |
NA |
NA |
199526.23 |
NA |
NA |
TTD |
| SCN4A |
(2R)-N-(2,6-dimethylphenyl)-N-methylpyrrolidine-2-carboxamide |
NA |
NA |
NA |
218776.16 |
NA |
NA |
TTD |
| SCN4A |
6-Phenoxy-2-piperazin-1-yl-1,3-benzothiazole |
NA |
250000 |
NA |
NA |
NA |
NA |
BindingDB |
| SCN4A |
Tonocard |
NA |
NA |
NA |
275422.87 |
NA |
NA |
TTD |
| SCN4A |
Propanamide, 2-amino-N-(2,6-dimethylphenyl)-, (S)- |
NA |
NA |
NA |
223872.11 |
NA |
NA |
TTD |
| SCN4A |
Ketamine |
NA |
2300000|800000 |
NA |
NA |
NA |
NA |
PubChem|TTD |
| SCN4A |
(7aR)-2-(2,6-dimethylphenyl)-5,6,7,7a-tetrahydro-3H-pyrrolo[1,2-c]imidazol-1-one |
NA |
NA |
NA |
501187.23 |
NA |
NA |
TTD |
| SCN4A |
6-Isopropyl-benzothiazol-2-ylamine |
NA |
118000 |
NA |
NA |
NA |
NA |
BindingDB |
| SCN4A |
(2R)-1-phenoxypropan-2-ol |
NA |
NA |
NA |
208929.61 |
NA |
NA |
TTD |
| SCN4A |
(2S)-1-phenoxypropan-2-ol |
NA |
NA |
NA |
234422.88 |
NA |
NA |
TTD |
| SCN4A |
Dofetilide |
NA |
300000 |
NA |
NA |
NA |
NA |
PubChem |
| SCN5A |
Linagliptin |
NA |
NA |
NA |
NA |
NA |
150000 |
PubChem |
| SCN5A |
N-[4-[[(5R)-2-methyl-5-phenyl-1,5-dihydro-2,4-benzodiazepin-3-yl]oxymethyl]phenyl]methanesulfonamide |
NA |
126000 |
NA |
NA |
NA |
NA |
TTD |
| SCN5A |
Tadalafil |
NA |
125893|158489|125892.54 |
NA |
NA |
NA |
NA |
PubChem|TTD |