| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| S1PR3 |
2-(2-Bromophenyl)-5-[(5,7-dichloro-2-methylquinolin-8-yl)oxymethyl]-1,3,4-oxadiazole |
NA |
NA |
NA |
222000 |
NA |
NA |
BindingDB |
| S1PR3 |
6-(cyclohexyl(cyclopropylmethyl)amino)-N-(4-((dimethylamino)methyl)phenyl)pyrimidine-4-carboxamide |
NA |
NA |
NA |
1014000 |
NA |
NA |
BindingDB |
| S1PR3 |
2-({4-[({6-[Cyclohexyl(cyclopropylmethyl)amino]pyrimidin-4-yl}carbonyl)amino]benzyl}amino)butanoic acid |
NA |
NA |
NA |
4890000 |
NA |
NA |
BindingDB |
| S1PR3 |
3-(4-(6-(Cyclohexyl(cyclopropylmethyl)amino)pyrimidine-4-carboxamido)benzylamino)propanoic acid |
NA |
NA |
NA |
1094000 |
NA |
NA |
BindingDB |
| S1PR3 |
1-[[4-[5-[Benzoyl(butyl)amino]-1,3,4-thiadiazol-2-yl]phenyl]methyl]azetidine-3-carboxylic acid |
NA |
NA |
NA |
400000 |
NA |
NA |
BindingDB|TTD |
| S1PR3 |
1-[[4-[5-[Butyl-(2-methoxybenzoyl)amino]-1,3,4-thiadiazol-2-yl]phenyl]methyl]azetidine-3-carboxylic acid |
NA |
NA |
NA |
427000 |
NA |
NA |
BindingDB|TTD |
| S1PR3 |
1-[[4-[5-[Butyl-(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]phenyl]methyl]azetidine-3-carboxylic acid |
NA |
NA |
NA |
720000 |
NA |
NA |
BindingDB|TTD |
| S1PR3 |
2-amino-N-(2-morpholinoethyl)-1-phenethyl-pyrrolo[3,2-b]quinoxaline-3-carboxamide |
NA |
NA |
NA |
178000 |
NA |
NA |
BindingDB |
| S1PR3 |
N-(1,8-dimethylpyrazolo[3,4-b]quinolin-3-yl)pyridine-2-carboxamide |
NA |
NA |
NA |
127000 |
NA |
NA |
BindingDB |
| S1PR3 |
2-[4-(6-Chloro-4-phenylquinazolin-2-yl)piperazin-1-yl]ethanol |
NA |
NA |
NA |
108000 |
NA |
NA |
BindingDB |
| S1PR4 |
[3-Hydroxy-4-(4-octylphenoxy)-butyl]-phosphonic acid |
NA |
NA |
NA |
440000 |
NA |
NA |
BindingDB|TTD |
| SAE1 |
Largazole |
NA |
450000 |
NA |
NA |
NA |
NA |
BindingDB |
| SARM1 |
Berberine Chloride |
130000|NA |
NA|110000|140000 |
NA |
NA |
NA |
NA |
PubChem |
| SARM1 |
Nitrofurazone |
120000 |
NA |
NA |
NA |
NA |
NA |
PubChem |
| SARM1 |
Doxycycline Hydrochloride |
NA|280000 |
145000|NA |
NA |
NA |
NA |
NA |
PubChem |
| SARM1 |
Phenazopyridine Hydrochloride |
NA |
145000 |
NA |
NA |
NA |
NA |
PubChem |
| SCN10A |
1-(2'',5''-bis(trifluoromethyl)biphenyl-3-yl)-1H-pyrazole-3,5-dicarboxamide |
NA |
2000000 |
NA |
NA |
NA |
NA |
TTD |
| SCN10A |
1-(2''-fluoro-3''-(trifluoromethoxy)biphenyl-3-yl)-1H-pyrazole-3,5-dicarboxamide |
NA |
1513000 |
NA |
NA |
NA |
NA |
TTD |
| SCN10A |
1-(2''-(trifluoromethoxy)-5''-(trifluoromethyl)biphenyl-3-yl)-1H-pyrazole-3,5-dicarboxamide |
NA |
1181000 |
NA |
NA |
NA |
NA |
TTD |
| SCN10A |
Dofetilide |
NA |
300000 |
NA |
NA |
NA |
NA |
PubChem |