| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| SCN8A |
3-(2,6-dimethylphenoxy)-N-[[4-(trifluoromethoxy)phenyl]methyl]propan-1-amine |
NA |
137800 |
NA |
NA |
NA |
NA |
BindingDB |
| SCN8A |
N-[(1-benzylindazol-3-yl)methyl]-3-(2,6-dimethylphenoxy)propan-1-amine |
NA |
287100 |
NA |
NA |
NA |
NA |
BindingDB |
| SCN8A |
Dofetilide |
NA |
300000 |
NA |
NA |
NA |
NA |
PubChem |
| SCN9A |
6-Phenoxy-2-piperazin-1-yl-1,3-benzothiazole |
NA |
106000 |
NA |
NA |
NA |
NA |
BindingDB |
| SCN9A |
Lacosamide |
NA |
182000 |
NA |
NA |
NA |
NA |
GtoPDB|PubChem |
| SCN9A |
Mexiletine |
NA |
340000|56000000 |
NA |
NA |
NA |
NA |
PubChem |
| SCN9A |
Dofetilide |
NA |
300000 |
NA |
NA |
NA |
NA |
PubChem |
| SDC2 |
(2S)-2-[[(2S)-3-(4-methoxyphenyl)-2-(3-oxo-1H-isoindol-2-yl)propanoyl]amino]propanoic acid |
NA |
128000 |
NA |
NA |
NA |
NA |
BindingDB |
| SDC2 |
(2S)-2-[[(2S)-3-(4-cyanophenyl)-2-(3-oxo-1H-isoindol-2-yl)propanoyl]amino]propanoic acid |
NA |
180000 |
NA |
NA |
NA |
NA |
BindingDB |
| SDC2 |
(2S)-2-[[(2S)-4-methyl-2-(3-oxo-1H-isoindol-2-yl)pentanoyl]amino]propanoic acid |
NA |
213000 |
NA |
NA |
NA |
NA |
BindingDB |
| SELE |
(2S)-3-methyl-2-[[(3R,5R)-1,3,4,5-tetrahydroxycyclohexanecarbonyl]amino]pentanoic acid |
NA |
50000000 |
NA |
NA |
NA |
NA |
TTD |
| SELE |
(2S)-3-hydroxy-2-[[(3R,5R)-1,3,4,5-tetrahydroxycyclohexanecarbonyl]amino]propanoic acid |
NA |
50000000 |
NA |
NA |
NA |
NA |
TTD |
| SELE |
(2R)-2-[(2S,3R,4S,5S,6R)-3-benzoyloxy-2-[(2R,3R)-1,4-dimethoxy-1,4-dioxo-3-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxybutan-2-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3-phenylpropanoic acid |
NA |
2080000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SELE |
(2R)-2-[(2S,3R,4S,5S,6R)-3,5-dibenzoyloxy-2-[(2R,3R)-1,4-dimethoxy-1,4-dioxo-3-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxybutan-2-yl]oxy-6-(hydroxymethyl)oxan-4-yl]oxy-3-phenylpropanoic acid |
NA |
140000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SELE |
(2R)-2-[(2S,3R,4S,5S,6R)-3-benzoyloxy-2-[(2R,3R)-1,4-dioxo-1,4-di(propan-2-yloxy)-3-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxybutan-2-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3-phenylpropanoic acid |
NA |
220000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SELE |
(4S)-5-(methylamino)-5-oxo-4-[[(2S)-2-(2-tetradecylhexadecanoylamino)-3-[(2S,3S,4S,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxypropanoyl]amino]pentanoic acid |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| SELE |
(4R)-5-(methylamino)-5-oxo-4-[[(2R)-2-(2-tetradecylhexadecanoylamino)-3-[(2S,3S,4S,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxypropanoyl]amino]pentanoic acid |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| SELE |
2,3,4-Trihydroxybenzoic Acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| SELE |
2-[3-[2-(3,4,5-Trihydroxybenzoyl)oxyphenyl]phenyl]acetic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| SELE |
4-Methyl-3-[2-(3,4,5-trihydroxy-phenyl)-acetylamino]-benzoic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |