| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| F2 |
2-[(S)-3-(3-Guanidino-propyl)-2,5-dioxo-piperazin-1-yl]-N-[(S)-4-guanidino-1-(thiazole-2-carbonyl)-butyl]-acetamide |
NA |
150000 |
NA |
NA |
NA |
NA |
TTD |
| F2 |
((S)-4-{[(S)-4-Guanidino-1-(thiazole-2-carbonyl)-butylcarbamoyl]-methyl}-3-oxo-1-phenylmethanesulfonyl-piperazin-2-yl)-acetic acid |
NA |
325000 |
NA |
NA |
NA |
NA |
TTD |
| F2 |
(2S)-1-[(2R)-2-(benzylsulfonylamino)-3-cyclohexylpropanoyl]-N-(5,6,7,8-tetrahydroquinazolin-6-ylmethyl)pyrrolidine-2-carboxamide |
289000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| F2 |
methyl (2S,4S)-4-amino-2-[[(2S,4S)-4-amino-2-[3-[(1R,3R)-3-[[(2S,4S)-4-amino-2-[[(2S,4S)-4-amino-5-(1H-indol-3-yl)-3-oxo-2-(phenylmethoxycarbonylamino)pentanoyl]amino]-5-(1H-indol-3-yl)-3-oxopentanoyl]amino]-2-oxocyclohexyl]propanoylamino]-5-(1H-indol-3-yl)-3-oxopentanoyl]amino]-5-(4-hydroxyphenyl)-3-oxopentanoate |
NA |
400000 |
NA |
NA |
NA |
NA |
TTD |
| F2 |
3-guanidinophenyl 6-(chloromethyl)-2-oxo-2H-chromene-3-carboxylate |
NA |
300000 |
NA |
NA |
NA |
NA |
TTD |
| F2 |
2-aminoethyl 6-(chloromethyl)-2-oxo-2H-chromene-3-carboxylate |
NA |
284000 |
NA |
NA |
NA |
NA |
TTD |
| F2 |
3-aminopropyl 6-(chloromethyl)-2-oxo-2H-chromene-3-carboxylate |
NA |
300000 |
NA |
NA |
NA |
NA |
TTD |
| F2 |
2-guanidinoethyl 6-(chloromethyl)-2-oxo-2H-chromene-3-carboxylate |
NA |
107000 |
NA |
NA |
NA |
NA |
TTD |
| F2 |
3-guanidinopropyl 6-(chloromethyl)-2-oxo-2H-chromene-3-carboxylate |
NA |
300000 |
NA |
NA |
NA |
NA |
TTD |
| F2 |
4-guanidinophenyl 6-(chloromethyl)-2-oxo-2H-chromene-3-carboxylate |
NA |
151000 |
NA |
NA |
NA |
NA |
TTD |
| F2 |
4-aminocyclohexyl 6-(chloromethyl)-2-oxo-2H-chromene-3-carboxylate |
NA |
300000 |
NA |
NA |
NA |
NA |
TTD |
| F2 |
piperidin-4-yl 6-(chloromethyl)-2-oxo-2H-chromene-3-carboxylate |
NA |
300000 |
NA |
NA |
NA |
NA |
TTD |
| F2 |
N-[(2S)-6-amino-1-[5-[[4-[2-(3,4-dichlorophenyl)ethoxy]phenyl]methyl]-1,2,4-oxadiazol-3-yl]-1-oxohexan-2-yl]-3,4-difluorobenzamide |
150000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| F2 |
N-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzyl]-guanidine |
NA |
129000 |
NA |
NA |
NA |
NA |
TTD |
| F2 |
2-[2-[(3-Carbamoylphenyl)carbamoyl]-4-(methylamino)phenyl]-5-(2-methylpropylcarbamoyl)benzoic acid |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| F2 |
2-[2-[(3-carbamoylphenyl)carbamoyl]-4-(methylamino)phenyl]-5-[[(1S)-1-carboxy-3-methylbutyl]carbamoyl]benzoic acid |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| F2 |
5-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]carbamoyl]-2-[2-[(3-carbamoylphenyl)carbamoyl]-4-(methylamino)phenyl]benzoic acid |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| F2 |
(2R)-2-(benzylsulfonylamino)-4-(1-oxidopyridin-1-ium-2-yl)-N-[2-oxo-2-(2-pyridin-4-ylethylamino)ethyl]butanamide |
1000000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| F2 |
2-(benzylsulfonylamino)-N-[2-[(5-chlorothiophen-2-yl)methylamino]-2-oxoethyl]-4-(1-oxidopyridin-1-ium-2-yl)butanamide |
190000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| F2 |
2-(benzylsulfonylamino)-4-(1-oxidopyridin-1-ium-2-yl)-N-[2-oxo-2-(thiophen-2-ylmethylamino)ethyl]butanamide |
140000 |
NA |
NA |
NA |
NA |
NA |
TTD |