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Drugs And Genes
Negative Drug Target Genes
Gene
Drug
GENE_SYMBOL
DRUG_NAME
Ki (nM)
IC50 (nM)
Kd (nM)
EC50 (nM)
Potency (nM)
AC50 (nM)
Datasource
ABCC8
Tifenazoxide
NA
165000|696000|685000
NA
NA
NA
NA
PubChem
ABCC8
Diazoxide
NA
740000|750000|198000|194000
NA
NA
NA
NA
PubChem
ABCG2
Amphotericitin B
NA
127000
NA
NA
NA
NA
BindingDB
ABCG2
5-[(3-bromophenyl)methoxy]-N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-4-oxochromene-2-carboxamide
NA
NA
NA
539510623
NA
NA
BindingDB
ABCG2
5-[(3-fluorophenyl)methoxy]-N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-4-oxochromene-2-carboxamide
NA
NA
NA
380189396
NA
NA
BindingDB
ABCG2
5-[(2-bromophenyl)methoxy]-N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-4-oxochromene-2-carboxamide
NA
NA
NA
85900000|85901352
NA
NA
BindingDB
ABCG2
5-[(4-bromophenyl)methoxy]-4-oxo-N-[2-(5-propan-2-yloxy-1H-indol-3-yl)ethyl]chromene-2-carboxamide
NA
NA
NA
359749335
NA
NA
BindingDB
ABCG2
5-[(2-fluorophenyl)methoxy]-N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-4-oxochromene-2-carboxamide
NA
NA
NA
549540874
NA
NA
BindingDB
ABCG2
5-[(4-bromophenyl)methoxy]-4-oxo-N-[2-(5-propoxy-1H-indol-3-yl)ethyl]chromene-2-carboxamide
NA
NA
NA
279898132
NA
NA
BindingDB
ABCG2
5-[(4-bromophenyl)methoxy]-N-[2-(1H-indol-3-yl)ethyl]-4-oxochromene-2-carboxamide
NA
NA
NA
959400632
NA
NA
BindingDB
ABCG2
5-[(4-fluorophenyl)methoxy]-N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-4-oxochromene-2-carboxamide
NA
NA
NA
260015956
NA
NA
BindingDB
ABCG2
N-(4-(2-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)phenyl)-2-nitrobenzamide
NA
109647.82
NA
NA
NA
NA
BindingDB
ABCG2
1,2-Dimethoxy-3-((2-(3-methoxyphenethyl)phenoxy)methyl)benzene
NA
NA|120000
NA
120000|NA
NA
NA
BindingDB|TTD
ABCG2
1,2-Dimethoxy-4-((2-(3-methoxyphenethyl)phenoxy)methyl)benzene
NA
NA|150000
NA
150000|NA
NA
NA
BindingDB|TTD
ABCG2
Caffeine
NA
14000000
NA
NA
NA
NA
BindingDB|PubChem
ABCG2
Verapamil
NA
524807
NA
NA
NA
NA
PubChem
ABCG2
Glyburide
NA
150000
NA
NA
NA
NA
BindingDB|PubChem
ABCG2
Diltiazem
NA
851138.04|851138
NA
NA
NA
NA
BindingDB|PubChem|TTD
ABCG2
Abacavir
NA
385000
NA
NA
NA
NA
BindingDB|PubChem
ABCG2
4-amino-N-(4-(2-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)phenyl)benzamide
NA
219000|263026.8
NA
NA
NA
NA
BindingDB|TTD
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