| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| ABL1 |
Mln8054 |
NA |
NA |
640000 |
NA |
NA |
NA |
BindingDB |
| ABL1 |
[4-[6-(4-Tert-butylanilino)pyrimidin-4-yl]phenyl]-[4-(2-fluorobenzoyl)piperazin-1-yl]methanone |
NA |
354000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ABL1 |
[4-[6-(3-Bromoanilino)pyrimidin-4-yl]phenyl]-[4-(2-fluorobenzoyl)piperazin-1-yl]methanone |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| ABL1 |
[4-[6-(2,4-Dichloroanilino)pyrimidin-4-yl]phenyl]-[4-(2-fluorobenzoyl)piperazin-1-yl]methanone |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| ABL1 |
[4-[6-(2-Chloroanilino)pyrimidin-4-yl]phenyl]-[4-(2-fluorobenzoyl)piperazin-1-yl]methanone |
NA |
141000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ABL1 |
[4-[6-(3,4-Difluoroanilino)pyrimidin-4-yl]phenyl]-[4-(2-fluorobenzoyl)piperazin-1-yl]methanone |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| ABL1 |
[4-(2-Fluorobenzoyl)piperazin-1-yl]-[4-[6-(3-propan-2-ylanilino)pyrimidin-4-yl]phenyl]methanone |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| ABL1 |
[4-[6-(4-Fluoroanilino)pyrimidin-4-yl]phenyl]-[4-(2-fluorobenzoyl)piperazin-1-yl]methanone |
NA |
277000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ABL1 |
[4-[6-(3-Chloro-4-methylanilino)pyrimidin-4-yl]phenyl]-[4-(2-fluorobenzoyl)piperazin-1-yl]methanone |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| ABL1 |
[4-[6-(3,4-Dichloroanilino)pyrimidin-4-yl]phenyl]-[4-(2-fluorobenzoyl)piperazin-1-yl]methanone |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| ABL1 |
[4-[6-(4-Tert-butylanilino)pyrimidin-4-yl]phenyl]-[4-(2-chlorobenzoyl)piperazin-1-yl]methanone |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| ABL1 |
[4-[6-(2,4-Dichloroanilino)pyrimidin-4-yl]phenyl]-[4-[3-(trifluoromethyl)benzoyl]piperazin-1-yl]methanone |
NA |
266000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ABL1 |
(4-Pyridin-2-ylphenyl)-[4-[3-(trifluoromethyl)benzoyl]piperazin-1-yl]methanone |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| ABL1 |
[4-(4-Tert-butylbenzoyl)piperazin-1-yl]-[4-(4-methylpyridin-2-yl)phenyl]methanone |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| ABL1 |
[4-(3-Fluorobenzoyl)piperazin-1-yl]-[4-(6-methylpyridin-3-yl)phenyl]methanone |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| ABL1 |
[4-[3-(Dimethylamino)benzoyl]piperazin-1-yl]-[4-(6-methylpyridin-3-yl)phenyl]methanone |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| ABL1 |
[4-(3-Fluorobenzoyl)piperazin-1-yl]-[4-(1,3-thiazol-2-yl)phenyl]methanone |
NA |
444180 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ABL1 |
[4-(2,4-Dichlorobenzoyl)piperazin-1-yl]-[4-(1,3-thiazol-2-yl)phenyl]methanone |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| ABL1 |
5-Bromo-2-chloro-4-[4-(4-fluorophenyl)sulfonylpiperazin-1-yl]pyrimidine |
NA |
122000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ABL1 |
12-Anilino-3,8-diphenyl-1,3,4,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-2(6),4,9,11-tetraen-7-one |
NA |
150000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |