| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| ABL1 |
Dasatinib |
NA |
5230000 |
NA |
NA |
NA |
NA |
PubChem |
| ABL1 |
8-(trifluoromethyl)-9H-purin-6-amine |
NA |
380000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ABL1 |
Kenpaullone |
NA |
350000 |
NA |
NA |
NA |
NA |
BindingDB |
| ABL1 |
N-[3-[(E)-2-[6-[3-(dimethylamino)propylamino]purin-9-yl]ethenyl]-4-methylphenyl]-3-(trifluoromethyl)benzamide |
NA |
157000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ABL1 |
(E)-3-(2-(6-(Cyclopropylamino)-9H-purin-9-yl)vinyl)-4-methyl-N-(2-fluoro-5-(trifluoromethyl)phenyl)benzamide |
NA |
236000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ABL1 |
N-(5-tert-butyl-2-methylpyrazol-3-yl)-3-[(E)-2-[6-(cyclopropylamino)purin-9-yl]ethenyl]-4-methylbenzamide |
NA |
146000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ABL1 |
(E)-N-(4-Methyl-3-(2-(6-(pyridine-2-yl-amino)-9H-purin-9-yl)vinyl)phenyl)-3-(trifluoromethyl)-benzamide |
NA |
243000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ABL1 |
N-(5-tert-butyl-1,3-thiazol-2-yl)-3-[(E)-2-[6-(cyclopropylamino)purin-9-yl]ethenyl]-4-methylbenzamide |
NA |
267000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ABL1 |
2-[(2-Oxo-2-phenylethyl)sulfanyl]-4-(3-thienyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile |
NA |
150000 |
NA |
NA |
NA |
NA |
TTD |
| ABL1 |
N-(4-methoxybenzyl)benzofuro[2,3-b]pyridin-4-amine |
NA |
392000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ABL1 |
3-(4-Methoxyphenyl)-2H-indeno[1,2-c]pyrazol-4-one |
NA |
725000 |
NA |
NA |
NA |
NA |
TTD |
| ABL1 |
1-[2-(Furan-2-yl)pyrrolidin-1-yl]prop-2-en-1-one |
1250000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| ABL1 |
Sunitinib |
NA |
NA |
890000 |
NA |
NA |
NA |
BindingDB |
| ABL1 |
Jnj-7706621 |
NA |
NA |
1200000 |
NA |
NA |
NA |
BindingDB |
| ABL1 |
Pelitinib |
NA |
NA |
230000 |
NA |
NA |
NA |
BindingDB |
| ABL1 |
6-(1,9-Diazaspiro[5.5]undecan-9-Yl)-9h-Purine |
NA |
126000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ABL1 |
|
NA |
NA |
2700000 |
NA |
NA |
NA |
BindingDB |
| ABL2 |
N-(4-methoxybenzyl)benzofuro[2,3-b]pyridin-4-amine |
1000000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| ABO |
9-[(2S,3S,4R)-2,3,4,5-tetrahydroxypentyl]-3,7-dihydropurine-2,6,8-trione |
361000|1500000 |
NA |
NA |
NA |
NA |
NA |
BindingDB |
| ABO |
3-(1,3,7-Trihydro-9-D-Ribityl-2,6,8-Purinetrione-7-Yl) |
NA|571000|2200000 |
NA |
2300000|NA |
NA |
NA |
NA |
BindingDB |