| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| ABL1 |
4-[5-Bromo-4-[4-[(3,5-dimethyl-1,2-oxazol-4-yl)sulfonyl]piperazin-1-yl]pyrimidin-2-yl]morpholine |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| ABL1 |
4-[4-(5-Bromo-2-morpholin-4-ylpyrimidin-4-yl)piperazin-1-yl]sulfonylbenzonitrile |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| ABL1 |
5-Bromo-2-chloro-4-(4-cyclopropylsulfonylpiperazin-1-yl)pyrimidine |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| ABL1 |
[4-(5-Bromo-2-morpholin-4-ylpyrimidin-4-yl)piperazin-1-yl]-(4-chloro-2-nitrophenyl)methanone |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| ABL1 |
4-[5-Bromo-4-[4-(2,5-dichlorothiophen-3-yl)sulfonylpiperazin-1-yl]pyrimidin-2-yl]morpholine |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| ABL1 |
6-[(2E)-2-[(4-fluorophenyl)methylidene]hydrazinyl]-1,5-diphenylpyrazolo[3,4-d]pyrimidin-4-one |
NA |
110000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ABL1 |
5-Bromo-2-chloro-4-(4-propylsulfonylpiperazin-1-yl)pyrimidine |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| ABL1 |
Pyrazolo[3,4-d]pyrimidin-4-one deriv. 4w |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| ABL1 |
2-(2-Chloro-phenyl)-5,7-dihydroxy-8-(3-hydroxy-1-methyl-piperidin-4-yl)-chromen-4-one |
NA |
110000 |
NA |
NA |
NA |
NA |
TTD |
| ABL1 |
(2R,4R)-4-[[3-(6-aminopyridin-3-yl)benzoyl]amino]-N-[4-chloro-3-(trifluoromethyl)phenyl]pyrrolidine-2-carboxamide |
NA |
103110 |
NA |
NA |
NA |
NA |
BindingDB |
| ABL1 |
N-[3-[2-(3-amino-1H-indazol-4-yl)ethynyl]phenyl]-3-(trifluoromethyl)benzamide |
NA |
2550000 |
NA |
NA |
NA |
NA |
BindingDB |
| ABL1 |
[4-[4-(3-amino-1H-indazol-4-yl)benzoyl]piperazin-1-yl]-(4-methylphenyl)methanone |
NA |
178660 |
NA |
NA |
NA |
NA |
BindingDB |
| ABL1 |
Canertinib |
NA |
NA |
200000 |
NA |
NA |
NA |
BindingDB |
| ABL1 |
Doramapimod |
NA |
NA |
6900000 |
NA |
NA |
NA |
BindingDB |
| ABL1 |
(2R,4R)-N-[4-chloro-3-(trifluoromethyl)phenyl]-4-[[3-[6-(2,2-dimethylpropanoylamino)pyridin-3-yl]benzoyl]amino]pyrrolidine-2-carboxamide |
NA |
147170 |
NA |
NA |
NA |
NA |
BindingDB |
| ABL1 |
N-[(2S)-1-[4-chloro-3-(trifluoromethyl)anilino]-1-oxopropan-2-yl]-3-[6-(2,2-dimethylpropanoylamino)pyridin-3-yl]benzamide |
NA |
243910 |
NA |
NA |
NA |
NA |
BindingDB |
| ABL1 |
N-[(2S)-1-[4-chloro-3-(trifluoromethyl)anilino]-1-oxopropan-2-yl]-3-[6-(methanesulfonamido)pyridin-3-yl]benzamide |
NA |
129310 |
NA |
NA |
NA |
NA |
BindingDB |
| ABL1 |
Erlotinib |
NA |
NA |
190000 |
NA |
NA |
NA |
BindingDB |
| ABL1 |
Sorafenib |
NA |
NA |
480000 |
NA |
NA |
NA |
BindingDB |
| ABL1 |
Neflamapimod |
NA |
NA |
2200000 |
NA |
NA |
NA |
BindingDB |