| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| ACHE |
(1S,13S,16S,18S)-18-methoxy-12,15-dimethyl-5,7-dioxa-12,15-diazapentacyclo[11.7.0.01,16.02,10.04,8]icosa-2,4(8),9,19-tetraen-14-one |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| ACHE |
(3R)-2'-bromo-8-hydroxyspiro[6,10,15-triazatetracyclo[7.6.1.02,7.012,16]hexadeca-1(15),2(7),4,8,10,12(16)-hexaene-3,4'-cyclohex-2-ene]-1'-one;2,2,2-trifluoroacetic acid |
NA |
116000 |
NA |
NA |
NA |
NA |
BindingDB |
| ACHE |
(1S,13R,16S,18S)-13-acetyl-18-methoxy-15-methyl-12-(3-methylbutyl)-5,7-dioxa-12,15-diazapentacyclo[11.7.0.01,16.02,10.04,8]icosa-2,4(8),9,19-tetraen-14-one |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| ACHE |
(1S,13S,16R,18S)-18-methoxy-15-methyl-12-(3-methylbutyl)-5,7-dioxa-12,15-diazapentacyclo[11.7.0.01,16.02,10.04,8]icosa-2,4(8),9,19-tetraen-11-one |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| ACHE |
(1S,13S,16S,18S)-18-methoxy-12,15-dimethyl-5,7-dioxa-12,15-diazapentacyclo[11.7.0.01,16.02,10.04,8]icosa-2,4(8),9,19-tetraene-11,14-dione |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| ACHE |
2',6'-Dibromospiro[6,10,15-triazatetracyclo[7.6.1.02,7.012,16]hexadeca-1(15),2(7),4,8,10,12(16)-hexaene-3,4'-cyclohexa-2,5-diene]-1',8-diol;2,2,2-trifluoroacetic acid |
NA |
152000 |
NA |
NA |
NA |
NA |
BindingDB |
| ACHE |
(4'S,6'S,8S)-6'-methoxy-4'-(methylamino)-6-(3-methylbutyl)spiro[5H-[1,3]dioxolo[4,5-g]isoquinoline-8,3'-cyclohexene]-7-one |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| ACHE |
(1S,12S,13S,16S,18S)-12-[2-(4-hydroxyphenyl)ethyl]-18-methoxy-15-methyl-12-oxido-5,7-dioxa-15-aza-12-azoniapentacyclo[11.7.0.01,16.02,10.04,8]icosa-2,4(8),9,19-tetraen-14-one |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| ACHE |
(1R,4R,12S,14S)-9-methoxy-4-methyl-4-oxido-11-oxa-4-azoniatetracyclo[8.6.1.01,12.06,17]heptadeca-6(17),7,9-trien-14-ol |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| ACHE |
(1S,12S,13S,16S,18S)-18-methoxy-15-methyl-12-oxido-12-(2-phenylethyl)-5,7-dioxa-15-aza-12-azoniapentacyclo[11.7.0.01,16.02,10.04,8]icosa-2,4(8),9,19-tetraen-14-one |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| ACHE |
N-[(1'S,5'S,8R)-5'-methoxy-6-(3-methylbutyl)spiro[5,7-dihydro-[1,3]dioxolo[4,5-g]isoquinoline-8,2'-cyclohex-3-ene]-1'-yl]-N-methylformamide |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| ACHE |
(1S,13S,16S,18S)-18-methoxy-15-methyl-12-(2-phenylethyl)-5,7-dioxa-12,15-diazapentacyclo[11.7.0.01,16.02,10.04,8]icosa-2,4(8),9,19-tetraen-14-one |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| ACHE |
(1S,13S,16S,18S)-18-methoxy-15-methyl-12-(3-methylbutyl)-5,7-dioxa-12,15-diazapentacyclo[11.7.0.01,16.02,10.04,8]icosa-2,4(8),9,19-tetraene-11,14-dione |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| ACHE |
4-Amino-2-[[hexyl(methyl)amino]methyl]phenol;dihydrochloride |
NA |
1053500 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
2-[4-(4-methoxyphenyl)phenoxy]-N-[3-(4-methylpiperazin-1-yl)propyl]acetamide |
NA |
190000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
4-Amino-2-[[butyl(methyl)amino]methyl]phenol;dihydrochloride |
NA |
125200 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
4-Amino-2-[(dimethylamino)methyl]phenol;dihydrochloride |
NA |
1536500 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
4-Amino-2-(pyrazol-1-ylmethyl)phenol;dihydrochloride |
NA |
844500 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
N-[3-(4-ethylpiperazin-1-yl)propyl]-2-[4-(4-methoxyphenyl)phenoxy]acetamide |
NA |
110000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
4-Amino-2-(methylaminomethyl)phenol;dihydrochloride |
NA |
333500 |
NA |
NA |
NA |
NA |
BindingDB|TTD |