Support By : Li-lab
| GENE_SYMBOL | DRUG_NAME | Ki (nM) | IC50 (nM) | Kd (nM) | EC50 (nM) | Potency (nM) | AC50 (nM) | Datasource |
|---|---|---|---|---|---|---|---|---|
| SORD | 7-Methoxycoumarin | NA | 124000 | NA | NA | NA | NA | BindingDB|TTD |
| SORD | 3-Hydroxycoumarin | NA | 106000 | NA | NA | NA | NA | BindingDB|TTD |
| SORD | Coumarin | NA | 400000 | NA | NA | NA | NA | PubChem|TTD |
| SORD | Quercetin | NA | 177000 | NA | NA | NA | NA | BindingDB|PubChem |
| SORD | Scopoletin | NA | 137000 | NA | NA | NA | NA | BindingDB|TTD |
| SORD | Hymecromone | NA | 153000 | NA | NA | NA | NA | BindingDB|PubChem|TTD |
| SORD | Umbelliferone | NA | 120000 | NA | NA | NA | NA | BindingDB|TTD |
| SORD | 6,7-Dihydroxy-4-methylcoumarin | NA | 212000 | NA | NA | NA | NA | BindingDB|TTD |
| SORD | Nordalbergin | NA | 288000 | NA | NA | NA | NA | BindingDB|TTD |
| SORD | 7-Hydroxycoumarin-4-acetic acid | NA | 163000 | NA | NA | NA | NA | BindingDB|TTD |
| SORD | 6,7-Dihydroxy-4-coumarinylacetic acid | NA | 335000 | NA | NA | NA | NA | BindingDB|TTD |
| SORD | 4-Hydroxycoumarins | NA | 400000 | NA | NA | NA | NA | TTD |
| SORD | Isoscopoletin | NA | 250000 | NA | NA | NA | NA | TTD |
| SORD | 6-hydroxy-2H-chromen-2-one | NA | 400000 | NA | NA | NA | NA | TTD |
| SORT1 | 3-(3-methylbutyl)-4H-1,2,4-oxadiazol-5-one | NA | 125893 | NA | NA | NA | NA | BindingDB |
| SORT1 | 2-Phenyl-1,3,4-oxadiazol-2-IN-5-one | NA | 125893 | NA | NA | NA | NA | BindingDB |
| SORT1 | 3-benzyl-4H-triazol-5-one | NA | 125893 | NA | NA | NA | NA | BindingDB |
| SORT1 | 3-Phenyl-5-isoxazolone | NA | 158489 | NA | NA | NA | NA | BindingDB |
| SOS1 | 3-(4-Chlorophenyl)-1H,4H,5H,6H,7H-pyrazolo[4,3-C]pyridine | NA | NA | 330000 | NA | NA | NA | BindingDB|ChEMBL |
| SOS1 | US20240059703, Example 1-32 | NA | 250000 | NA | NA | NA | NA | BindingDB |