| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| SOS1 |
US20240059703, Example 1-33 |
NA |
174000 |
NA |
NA |
NA |
NA |
BindingDB |
| SOS1 |
US20240059703, Example 2-43 |
NA |
131000 |
NA |
NA |
NA |
NA |
BindingDB |
| SOS1 |
US20240059703, Example 5 |
NA |
181000 |
NA |
NA |
NA |
NA |
BindingDB |
| SOS1 |
US20240059703, Example 13-112 |
NA |
153000 |
NA |
NA |
NA |
NA |
BindingDB |
| SOS1 |
US20240059703, Example 14-15 |
NA |
250000 |
NA |
NA |
NA |
NA |
BindingDB |
| SOS1 |
US20240059703, Example 13-55 |
NA |
141000 |
NA |
NA |
NA |
NA |
BindingDB |
| SOS1 |
US20240059703, Example 13-139 |
NA |
167000 |
NA |
NA |
NA |
NA |
BindingDB |
| SOS1 |
US20240059703, Example 23-29 |
NA |
127140 |
NA |
NA |
NA |
NA |
BindingDB |
| SOS1 |
US20240059703, Example 13-102 |
NA |
140000 |
NA |
NA |
NA |
NA |
BindingDB |
| SOS1 |
US20240059703, Example 13-154 |
NA |
139900 |
NA |
NA |
NA |
NA |
BindingDB |
| SOS1 |
1-[(4-fluorophenyl)methyl]-2-methyl-4-nitro-1H-imidazole |
NA |
NA |
1200000 |
NA |
NA |
NA |
BindingDB|ChEMBL |
| SOS1 |
{[5-(3-Chlorophenyl)furan-2-YL]methyl}(methyl)amine |
NA |
NA |
730000 |
NA |
NA |
NA |
BindingDB|ChEMBL |
| SOS1 |
1-ethyl-N-(naphthalen-1-ylmethyl)-1H-tetrazol-5-amine |
NA |
NA |
1400000 |
NA |
NA |
NA |
BindingDB|ChEMBL |
| SOS1 |
6-Chloro-2-(piperazin-1-ylmethyl)-1,3-benzoxazole |
NA |
NA |
1900000 |
NA |
NA |
NA |
BindingDB|ChEMBL |
| SOS1 |
1-(4-Chlorophenylmethyl)-2-aminobenzimidazole |
NA |
NA |
350000 |
NA |
NA |
NA |
BindingDB|ChEMBL |
| SOS1 |
4-Phenoxybenzenesulfonamide |
NA |
NA |
600000|6e+05 |
NA |
NA |
NA |
BindingDB|ChEMBL |
| SPHK2 |
(2S,3S)-3-(dimethylamino)-1-tetradecoxybutan-2-ol |
NA |
300000 |
NA |
NA |
NA |
NA |
TTD |
| SPHK2 |
Spisulosine |
NA |
766000 |
NA |
NA |
NA |
NA |
TTD |
| SQLE |
3,7,11,16,20,24-Hexamethyl-pentacosa-1,3,7,11,15,19,23-heptaene |
NA |
400000 |
NA |
NA |
NA |
NA |
TTD |
| SQLE |
1,1,22,22-Tetrachloro-5,9,14,18-tetramethyl-docosa-1,5,9,13,17,21-hexaene |
NA |
400000 |
NA |
NA |
NA |
NA |
TTD |