| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| TSPO |
Norflunitrazepam |
NA |
666806769.2 |
NA |
NA |
NA |
NA |
TTD |
| TSPO |
5-(2-Chlorophenyl)-1,3-dihydro-1-methyl-7-nitro-2H-1,4-benzodiazepin-2-one |
NA |
454988060.2 |
NA |
NA |
NA |
NA |
TTD |
| TSPO |
Temazepam |
NA |
62517300|62517269.28 |
NA |
NA |
NA |
NA |
PubChem|TTD |
| TSPO |
2H-1,4-Benzodiazepin-2-one, 7-chloro-1-(1,1-dimethylethyl)-1,3-dihydro-5-phenyl- |
NA |
1614358.56 |
NA |
NA |
NA |
NA |
TTD |
| TSPO |
Motrazepam |
NA |
2328091.26 |
NA |
NA |
NA |
NA |
TTD |
| TSPO |
7-Fluoro-5-phenyl-1,3-dihydro-2h-1,4-benzodiazepin-2-one |
NA |
25003453.62 |
NA |
NA |
NA |
NA |
TTD |
| TSPO |
RO-05-2921 |
NA |
2857590.54 |
NA |
NA |
NA |
NA |
TTD |
| TSPO |
7-Aminonitrazepam |
NA |
2588212.92 |
NA |
NA |
NA |
NA |
TTD |
| TSPO |
7-Aminoflunitrazepam |
NA |
15381500|15381546.4 |
NA |
NA |
NA |
NA |
PubChem|TTD |
| TSPO |
7-Chloro-5-(2,6-dichlorophenyl)-1-methyl-1H-benzo[e][1,4]diazepin-2(3H)-one |
NA |
181970085.9 |
NA |
NA |
NA |
NA |
TTD |
| TTK |
3-amino-5-[4-[(dimethylamino)methyl]phenyl]-1H-pyridin-2-one |
367300 |
NA |
NA |
NA |
NA |
NA |
BindingDB|ChEMBL|TTD |
| TTK |
3-amino-5-pyrimidin-5-yl-1H-pyridin-2-one |
269300 |
NA |
NA |
NA |
NA |
NA |
BindingDB|ChEMBL|TTD |
| TTK |
5-amino-1-methyl-[3,4'-bipyridin]-6(1H)-one |
236400 |
NA |
NA |
NA |
NA |
NA |
BindingDB|ChEMBL|TTD |
| TTK |
3-amino-5-phenyl-1H-pyridin-2-one |
128200 |
NA |
NA |
NA |
NA |
NA |
BindingDB|ChEMBL|TTD |
| TTK |
3-Amino-2-pyridinol |
1000000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| TTL |
3-Formyltyrosine |
300000 |
NA |
NA |
NA |
NA |
NA |
BindingDB |
| TTL |
2-Amino-3-(3-azido-4-hydroxyphenyl)propanoic acid |
200000 |
NA |
NA |
NA |
NA |
NA |
BindingDB |
| TTL |
2-Amino-3-(4-hydroxy-3-nitrophenyl)propanoic acid |
400000 |
NA |
NA |
NA |
NA |
NA |
BindingDB |
| TTL |
3-Aminotyrosine |
200000 |
NA |
NA |
NA |
NA |
NA |
BindingDB |
| TTL |
(2S)-2-[(E,1S)-5-[(1S,3S,4R,8S,9R,10R,12R)-3,10-dihydroxy-4,8,10-trimethyl-2-oxatricyclo[6.3.1.04,12]dodecan-9-yl]-1-hydroxy-3-methylpent-2-enyl]-3-methyl-2H-furan-5-one |
NA |
NA |
210000 |
NA |
NA |
NA |
BindingDB |