| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| TUBB6 |
Colchicine |
NA |
800000 |
NA |
NA |
NA |
NA |
PubChem |
| TUBB8 |
Podofilox |
NA |
460000 |
NA |
NA |
NA |
NA |
PubChem |
| TUBB8 |
Noscapine |
NA |
NA |
144000 |
NA |
NA |
NA |
PubChem |
| TUBB8 |
Griseofulvin |
NA |
NA |
300000 |
NA |
NA |
NA |
PubChem |
| TUBB8 |
Colchicine |
NA |
800000 |
NA |
NA |
NA |
NA |
PubChem |
| TXK |
Tak-020 |
NA |
6309570 |
NA |
NA |
NA |
NA |
PubChem |
| TXNRD1 |
Ligustrazine |
NA |
200000 |
NA |
NA |
NA |
NA |
PubChem |
| TXNRD1 |
(3R,6S)-1-benzyl-4-cyclohexyl-6-[2-(4-methylphenyl)-2-oxoethyl]-3-pyridin-3-ylpiperazine-2,5-dione |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| TXNRD1 |
(2E)-N-[2-(Cyclohexylamino)-1-(4-methoxyphenyl)-2-oxoethyl]-N-isobutyl-4-(4-methylphenyl)-4-oxo-2-butenamide |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| TXNRD1 |
N-tert-butyl-3,3-dimethyl-2-[[(E)-4-(4-methylphenyl)-4-oxobut-2-enoyl]-(2-methylpropyl)amino]butanamide |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| TXNRD1 |
Ellagic Acid |
NA |
275300 |
NA |
NA |
NA |
NA |
PubChem |
| TXNRD2 |
Ligustrazine |
NA |
200000 |
NA |
NA |
NA |
NA |
PubChem |
| TXNRD2 |
Ellagic Acid |
NA |
275300 |
NA |
NA |
NA |
NA |
PubChem |
| TXNRD3 |
Ligustrazine |
NA |
200000 |
NA |
NA |
NA |
NA |
PubChem |
| TXNRD3 |
Ellagic Acid |
NA |
275300 |
NA |
NA |
NA |
NA |
PubChem |
| TYK2 |
1H-Pyrrole-3-carboxamide, 5-((5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl)-N-((2S)-2-hydroxy-3-(4-morpholinyl)propyl)-2,4-dimethyl- |
5100000 |
NA |
NA |
NA |
NA |
NA |
BindingDB |
| TYK2 |
Ast-487 |
2100000 |
NA |
NA |
NA |
NA |
NA |
BindingDB |
| TYK2 |
N-butyl-N-methyl-1-[3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclobutyl]methanesulfonamide |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| TYK2 |
N-[3-(benzenesulfonylmethyl)cyclobutyl]-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| TYK2 |
4-N-cyclohexyl-2-N-(2-methoxy-4-morpholin-4-ylphenyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine |
NA |
132000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |