| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| ADORA2B |
(2S,3S,4R,5R)-N-ethyl-3,4-dihydroxy-5-[6-[[(1R,2R)-2-hydroxycyclopentyl]amino]purin-9-yl]oxolane-2-carboxamide |
NA |
NA |
NA |
331131.12 |
NA |
NA |
TTD |
| ADORA2B |
2-(2-Phenylethoxy)adenosine |
NA |
NA |
NA |
286418 |
NA |
NA |
BindingDB |
| ADORA2B |
Pyrido[2,3-g]quinoline-5,10-dione |
NA |
NA |
NA |
331131 |
NA |
NA |
BindingDB |
| ADORA2B |
1,3-dimethyl-8-[(4-phenyl-1,2-oxazol-3-yl)methyl]-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione |
300000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| ADORA2B |
1-deoxy-1-{6-[N''-(5-methyl-thiophene-2-carbonyl)-hydrazino]-9H-purin-9-yl}-N-ethyl-beta-Dribofuranuronamide |
NA |
NA |
NA |
3664376 |
NA |
NA |
BindingDB |
| ADORA2B |
(2S,3S,4R,5R)-5-[2-chloro-6-[2-(furan-2-carbonyl)hydrazinyl]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide |
NA |
NA |
NA |
4764310 |
NA |
NA |
BindingDB |
| ADORA2B |
(2S,3S,4R,5R)-5-[2-chloro-6-[2-(2-thiophen-2-ylacetyl)hydrazinyl]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide |
NA |
NA |
NA |
1659587 |
NA |
NA |
BindingDB |
| ADORA2B |
1-deoxy-1-{6-[N''-(furan-2-carbonyl)-hydrazino]-9H-purin-9-yl}-N-ethyl-beta-D-ribofuranuronamide |
NA |
NA |
NA |
12189896 |
NA |
NA |
BindingDB |
| ADORA2B |
(2S,3S,4R,5R)-5-[6-[2-(5-bromofuran-2-carbonyl)hydrazinyl]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide |
NA |
NA |
NA |
2710192 |
NA |
NA |
BindingDB |
| ADORA2B |
(2S,3S,4R,5R)-N-ethyl-3,4-dihydroxy-5-[6-[2-(5-methylfuran-2-carbonyl)hydrazinyl]purin-9-yl]oxolane-2-carboxamide |
NA |
NA |
NA |
4405549 |
NA |
NA |
BindingDB |
| ADORA2B |
1-deoxy-1-{2-chloro-6-[N''-(thiophene-3-carbonyl)-hydrazino]-9H-purin-9-yl}-N-ethyl-beta-D-ribofuranuronamide |
NA |
NA |
NA |
2223310 |
NA |
NA |
BindingDB |
| ADORA2B |
1-deoxy-1-{2-chloro-6-[N''-(thiophene-2-carbonyl)-hydrazino]-9H-purin-9-yl}-N-ethyl-beta-D-ribofuranuronamide |
NA |
NA |
NA |
5000345 |
NA |
NA |
BindingDB |
| ADORA2B |
(2S,3S,4R,5R)-5-[2-chloro-6-[2-(3-methylthiophene-2-carbonyl)hydrazinyl]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide |
NA |
NA |
NA |
2937650 |
NA |
NA |
BindingDB |
| ADORA2B |
(2S,3S,4R,5R)-5-[2-chloro-6-[2-(1H-pyrrole-2-carbonyl)hydrazinyl]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide |
NA |
NA |
NA |
2786121 |
NA |
NA |
BindingDB |
| ADORA2B |
(2R,3R,4S,5R)-2-(6-amino-2-(2-(5-chloro-1H-indol-3-yl)ethoxy)-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol |
NA |
NA |
NA |
458142 |
NA |
NA |
BindingDB |
| ADORA2B |
(2R,3R,4S,5R)-2-(6-amino-2-(2-(5-iodo-1H-indol-3-yl)ethoxy)-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol |
NA |
NA |
NA |
534564 |
NA |
NA |
BindingDB |
| ADORA2B |
(2R,3R,4S,5R)-2-(6-amino-2-(2-(6-chloro-1H-indol-3-yl)ethoxy)-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol |
NA |
NA |
NA |
4623810 |
NA |
NA |
BindingDB |
| ADORA2B |
(2R,3R,4S,5R)-2-(6-amino-2-(2-(5-hydroxy-1H-indol-3-yl)ethoxy)-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol |
NA |
NA |
NA |
1116863 |
NA |
NA |
BindingDB |
| ADORA2B |
(2R,3R,4S,5R)-2-(2-(2-(1H-indol-3-yl)ethoxy)-6-amino-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol |
NA |
NA |
NA |
3341950 |
NA |
NA |
BindingDB |
| ADORA2B |
(2R,3R,4S,5R)-2-(6-amino-2-(2-(5-fluoro-1H-indol-3-yl)ethoxy)-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol |
NA |
NA |
NA |
1303167 |
NA |
NA |
BindingDB |