| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| ADORA2B |
(2S,3S,4R,5R)-5-(6-(4-(2-(4-chlorophenylamino)-2-oxoethoxy)phenylamino)-9H-purin-9-yl)-N-ethyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide |
NA |
NA |
NA |
81283052 |
NA |
NA |
BindingDB |
| ADORA2B |
(2S,3S,4R,5R)-5-(6-(4-(2-(4-bromophenylamino)-2-oxoethoxy)phenylamino)-9H-purin-9-yl)-N-ethyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide |
NA |
NA |
NA |
95279616 |
NA |
NA |
BindingDB |
| ADORA2B |
(2S,3S,4R,5R)-N-ethyl-3,4-dihydroxy-5-(6-(4-(2-(4-iodophenylamino)-2-oxoethoxy)phenylamino)-9H-purin-9-yl)-tetrahydrofuran-2-carboxamide |
NA |
NA |
NA |
33113112 |
NA |
NA |
BindingDB |
| ADORA2B |
(2S,3S,4R,5R)-N-ethyl-3,4-dihydroxy-5-(6-(4-(2-(4-methoxyphenylamino)-2-oxoethoxy)phenylamino)-9H-purin-9-yl)-tetrahydrofuran-2-carboxamide |
NA |
NA |
NA |
30831880 |
NA |
NA |
BindingDB |
| ADORA2B |
(2S,3S,4R,5R)-5-(6-(4-(2-(3,4-dimethoxyphenylamino)-2-oxoethoxy)phenylamino)-9H-purin-9-yl)-N-ethyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide |
NA |
NA |
NA |
22029265 |
NA |
NA |
BindingDB |
| ADORA2B |
(2S,3S,4R,5R)-5-(6-(4-(2-(3,5-dimethoxyphenylamino)-2-oxoethoxy)phenylamino)-9H-purin-9-yl)-N-ethyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide |
NA |
NA |
NA |
18663797 |
NA |
NA |
BindingDB |
| ADORA2B |
(2S,3S,4R,5R)-5-(6-(4-(2-(benzo[d][1,3]dioxol-5-ylamino)-2-oxoethoxy)phenylamino)-9H-purin-9-yl)-N-ethyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide |
NA |
NA |
NA |
28183829 |
NA |
NA |
BindingDB |
| ADORA2B |
(2S,3S,4R,5R)-5-(6-(4-(2-(4-tert-butylphenylamino)-2-oxoethoxy)phenylamino)-9H-purin-9-yl)-N-ethyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide |
NA |
NA |
NA |
60953690 |
NA |
NA |
BindingDB |
| ADORA2B |
(2S,3S,4R,5R)-N-ethyl-3,4-dihydroxy-5-(6-(4-(2-(4-morpholinophenylamino)-2-oxoethoxy)phenylamino)-9H-purin-9-yl)-tetrahydrofuran-2-carboxamide |
NA |
NA |
NA |
3334264 |
NA |
NA |
BindingDB |
| ADORA2B |
(2S,3S,4R,5R)-N-ethyl-3,4-dihydroxy-5-(6-(4-(2-oxo-2-(pyridin-4-ylamino)ethoxy)phenylamino)-9H-purin-9-yl)-tetrahydrofuran-2-carboxamide |
NA |
NA |
NA |
30974193 |
NA |
NA |
BindingDB |
| ADORA2B |
(2S,3S,4R,5R)-5-(6-(4-(2-(benzylamino)-2-oxoethoxy)phenylamino)-9H-purin-9-yl)-N-ethyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide |
NA |
NA |
NA |
6668068 |
NA |
NA |
BindingDB |
| ADORA2B |
(2S,3S,4R,5R)-5-(6-(4-(2-(4-methoxybenzylamino)-2-oxoethoxy)phenylamino)-9H-purin-9-yl)-N-ethyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide |
NA |
NA |
NA |
4168694 |
NA |
NA |
BindingDB |
| ADORA2B |
(2S,3S,4R,5R)-5-(6-(4-(2-(cyclohexylamino)-2-oxoethoxy)phenylamino)-9H-purin-9-yl)-N-ethyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide |
NA |
NA |
NA |
3176874 |
NA |
NA |
BindingDB |
| ADORA2B |
(2S,3S,4R,5R)-5-(2-chloro-6-(4-(2-oxo-2-(phenylamino)ethoxy)phenylamino)-9H-purin-9-yl)-N-ethyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide |
NA |
NA |
NA |
23496328 |
NA |
NA |
BindingDB |
| ADORA2B |
(2S,3S,4R,5R)-5-(2-chloro-6-(4-(2-(4-methoxyphenylamino)-2-oxoethoxy)phenylamino)-9H-purin-9-yl)-N-ethyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide |
NA |
NA |
NA |
2779713 |
NA |
NA |
BindingDB |
| ADORA2B |
(2S,3S,4R,5R)-5-(6-(4-(2-(benzylamino)-2-oxoethoxy)phenylamino)-2-chloro-9H-purin-9-yl)-N-ethyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide |
NA |
NA |
NA |
5714786 |
NA |
NA |
BindingDB |
| ADORA2B |
(2S,3S,4R,5R)-5-(2-chloro-6-(4-(2-(cyclohexylamino)-2-oxoethoxy)phenylamino)-9H-purin-9-yl)-N-ethyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide |
NA |
NA |
NA |
3311311 |
NA |
NA |
BindingDB |
| ADORA2B |
(2S,3S,4R,5R)-5-[2-chloro-6-[2-(5-methyl-1H-pyrrole-2-carbonyl)hydrazinyl]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide |
NA |
NA |
NA |
5714786 |
NA |
NA |
BindingDB |
| ADORA2B |
(2R,3R,4S,5R)-2-[6-amino-2-[(3S)-3-hydroxy-3-phenylprop-1-ynyl]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol |
NA |
NA |
NA |
1086426 |
NA |
NA |
BindingDB |
| ADORA2B |
(2S,3S,4R,5R)-N-ethyl-3,4-dihydroxy-5-[6-[4-[2-[4-iodo-2-(trifluoromethyl)anilino]-2-oxoethoxy]anilino]purin-9-yl]oxolane-2-carboxamide |
NA |
NA |
NA |
9354057 |
NA |
NA |
BindingDB |