| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| ADORA2B |
(2R,3R,4S,5R)-2-[6-amino-2-(2-naphthalen-1-ylethoxy)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol |
NA |
NA |
NA |
695024 |
NA |
NA |
BindingDB |
| ADORA2B |
6-guanidino-NECA |
NA |
NA |
NA |
18365383 |
NA |
NA |
BindingDB |
| ADORA2B |
5'-N-Ethylcarboxamidoadenosine |
NA |
NA |
NA |
7144963 |
NA |
NA |
BindingDB |
| ADORA2B |
Theobromine |
NA |
130000 |
NA |
NA |
NA |
NA |
BindingDB|PubChem |
| ADORA2B |
5-Phenyl-1,2,4-thiadiazol-3-amine |
NA |
NA |
107700 |
NA |
NA |
NA |
BindingDB|ChEMBL |
| ADORA2B |
(2R,3R,4S,5R)-2-(6-Amino-2-{N''-[1-cyclohexyl-meth-(Z)-ylidene]-hydrazino}-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol |
430000 |
NA |
NA |
NA |
NA |
NA |
BindingDB |
| ADORA2B |
Xanthine amine congener |
141000 |
NA |
NA |
NA |
NA |
NA |
BindingDB |
| ADORA2B |
(2R,3R,4S,5R)-2-[6-amino-2-[(2Z)-2-(cyclohexylmethylidene)hydrazinyl]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol |
430000 |
NA |
NA |
NA |
NA |
NA |
GtoPDB |
| ADORA2B |
3-Methylxanthine |
133000|240000 |
NA |
NA |
NA |
NA |
NA |
PubChem |
| ADORA2B |
2,4-Diamino-6-phenyl-1,3,5-triazine |
NA |
NA |
107000 |
NA |
NA |
NA |
BindingDB|ChEMBL |
| ADORA2B |
2-Chloroadenosine |
NA |
NA |
NA |
188799 |
NA |
NA |
BindingDB |
| ADORA2B |
(R)-N-(1-Methyl-2-phenylethyl)adenosine |
NA |
NA |
NA |
595662 |
NA |
NA |
BindingDB |
| ADORA2B |
Binodenoson |
430000 |
NA |
NA |
NA |
NA |
NA |
PubChem |
| ADORA2B |
N(6)-Cyclohexyladenosine |
160000 |
NA |
NA |
NA |
NA |
NA |
GtoPDB |
| ADORA2B |
4-(6-Cyclopentylamino-purin-9-yl)-1-hydroxymethyl-bicyclo[3.1.0]hexane-2,3-diol |
139000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ADORA2B |
(2R,3R,4S,5R)-2-[6-amino-2-[(3R)-3-hydroxy-3-phenylprop-1-ynyl]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol |
NA |
NA |
NA |
161436 |
NA |
NA |
BindingDB |
| ADORA3 |
2-(4-Hydroxy-phenyl)-2H,5H-[1,2,4]triazolo[4,3-a]quinoxaline-1,4-dione |
4330000 |
NA |
NA |
NA |
NA |
NA |
BindingDB |
| ADORA3 |
2-(4-Methoxy-phenyl)-2H,5H-[1,2,4]triazolo[4,3-a]quinoxaline-1,4-dione |
4790000 |
NA |
NA |
NA |
NA |
NA |
BindingDB |
| ADORA3 |
4-methyl-N'-(3-pyridin-2-ylisoquinolin-1-yl)benzenecarboximidamide |
580000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ADORA3 |
3-Chloro-N-[3-(2-pyridinyl)-1-isoquinolinyl]benzamide |
770000 |
NA |
NA |
NA |
NA |
NA |
BindingDB |