| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| ADORA3 |
1-Phenyl-3-(2-pyridin-4-yl-quinazolin-4-yl)-urea |
336000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ADORA3 |
3-Benzylsulfanyl-4-oxo-4,5,6,7-tetrahydro-benzo[c]thiophene-1-carboxylic acid |
117000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ADORA3 |
4-amino-2-(4-methoxyphenyl)-[1,2,4]triazolo[4,3-a]quinoxalin-1(2H)-one |
4340000 |
NA |
NA |
NA |
NA |
NA |
BindingDB |
| ADORA3 |
1-(4-Methoxy-phenyl)-3-(4-pyridin-2-yl-thiazol-2-yl)-urea |
147000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ADORA3 |
1-Phenyl-3-(2-(pyridin-2-yl)quinazolin-4-yl)urea |
495000 |
NA |
NA |
NA |
NA |
NA |
BindingDB |
| ADORA3 |
1-(2-Furan-2-yl-quinazolin-4-yl)-3-phenyl-urea |
257000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ADORA3 |
2-(furan-2-yl)-8-(3-phenylpropyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine |
426579.52 |
NA |
NA |
NA |
NA |
NA |
BindingDB |
| ADORA3 |
1-Methoxymethyl-2-methyl-6-phenyl-4-phenylethynyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-(2-trimethylsilanyl-ethyl) ester |
170000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ADORA3 |
2-(4-Amino-phenyl)-2H,5H-[1,2,4]triazolo[4,3-a]quinoxaline-1,4-dione |
2440000 |
NA |
NA |
NA |
NA |
NA |
BindingDB |
| ADORA3 |
1-(2-Chloro-phenyl)-3-(2-phenyl-quinazolin-4-yl)-urea |
220000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ADORA3 |
2-Furan-2-yl-8-(2,4,5-tribromo-benzyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine |
4466835.92 |
NA |
NA |
NA |
NA |
NA |
BindingDB |
| ADORA3 |
Amino-8-propyl-2-(2-furyl) pyrazolo (4,3-e)-1,2,4-triazolo (1,5-c)pyrimidine |
331131.12 |
NA |
NA |
NA |
NA |
NA |
BindingDB |
| ADORA3 |
1-[2-(6-Methyl-pyridin-2-yl)-quinazolin-4-yl]-3-phenyl-urea |
264000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ADORA3 |
4-methoxy-N-(2-pyridin-2-ylquinazolin-4-yl)benzamide |
150000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ADORA3 |
1-(3-Methoxy-phenyl)-3-(2-phenyl-quinazolin-4-yl)-urea |
2040000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ADORA3 |
4-(Furan-2-yl)-11-(2-naphthalen-1-ylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine |
3388441.56 |
NA |
NA |
NA |
NA |
NA |
BindingDB |
| ADORA3 |
4-(Furan-2-yl)-11-(3-methylbut-2-enyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine |
812830.52 |
NA |
NA |
NA |
NA |
NA |
BindingDB |
| ADORA3 |
2-(furan-2-yl)-8-isopentyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine |
707945.78 |
NA |
NA |
NA |
NA |
NA |
BindingDB |
| ADORA3 |
1-Phenyl-2-(3-pyridin-2-yl-isoquinolin-1-yl)-propan-1-one |
370000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ADORA3 |
2-(4-Ethoxy-phenyl)-2H,5H-[1,2,4]triazolo[4,3-a]quinoxaline-1,4-dione |
3750000 |
NA |
NA |
NA |
NA |
NA |
BindingDB |