| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| ADORA3 |
N-(3-Pyridin-2-yl-isoquinolin-1-yl)-acetamide |
13000000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ADORA3 |
4-chloro-N-(3-(pyridin-2-yl)isoquinolin-1-yl)benzamide |
200000 |
NA |
NA |
NA |
NA |
NA |
BindingDB |
| ADORA3 |
3,4-Dichloro-N-(3-pyridin-2-yl-isoquinolin-1-yl)-benzamide |
210000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ADORA3 |
3-methyl-N-(3-(pyridin-2-yl)isoquinolin-1-yl)benzamide |
240000 |
NA |
NA |
NA |
NA |
NA |
BindingDB |
| ADORA3 |
3-methoxy-N-(3-(pyridin-2-yl)isoquinolin-1-yl)benzamide |
150000 |
NA |
NA |
NA |
NA |
NA |
BindingDB |
| ADORA3 |
2,4-dimethyl-N-(3-(pyridin-2-yl)isoquinolin-1-yl)benzamide |
360000 |
NA |
NA |
NA |
NA |
NA |
BindingDB |
| ADORA3 |
2,5-Dimethyl-N-(3-pyridin-2-yl-isoquinolin-1-yl)-benzamide |
430000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ADORA3 |
2,6-Dimethyl-N-(3-pyridin-2-yl-isoquinolin-1-yl)-benzamide |
2600000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ADORA3 |
3,5-Dimethyl-N-(3-pyridin-2-yl-isoquinolin-1-yl)-benzamide |
320000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ADORA3 |
US10428083, Example 86 |
160000 |
NA |
NA |
NA |
NA |
NA |
BindingDB |
| ADORA3 |
3-(4-Methylphenyl)-8-(2-oxopropoxy)chromen-2-one |
634000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ADORA3 |
N-benzyl-2-[[2-[2-[[2,6-bis(4-methoxyphenyl)pyrimidin-4-yl]amino]-2-oxoethoxy]acetyl]amino]acetamide |
185200 |
NA |
NA |
NA |
NA |
NA |
BindingDB |
| ADORA3 |
Enprofylline |
158000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|PubChem |
| ADORA3 |
N-(furan-2-ylmethyl)-1-propan-2-ylpyrazolo[3,4-b]pyridine-5-carboxamide |
NA |
NA |
400000|4e+05 |
NA |
NA |
NA |
BindingDB|ChEMBL |
| ADORA3 |
2-(Benzylamino)pyrido[1,2-a]pyrimidin-4-one |
NA |
NA |
200000|2e+05 |
NA |
NA |
NA |
BindingDB|ChEMBL |
| ADORA3 |
3-Phenyl-[1,2,4]triazolo[4,3-b]pyridazin-6-amine |
NA |
NA |
160000 |
NA |
NA |
NA |
BindingDB|ChEMBL |
| ADORA3 |
5-methyl-2-phenyl-2H-1,2,3-triazole-4-carboxamide |
NA |
NA |
101000 |
NA |
NA |
NA |
BindingDB|ChEMBL |
| ADORA3 |
N-benzyl-2,1,3-benzoxadiazole-5-carboxamide |
NA |
NA |
180000 |
NA |
NA |
NA |
BindingDB|ChEMBL |
| ADORA3 |
Cefazolin |
NA |
NA |
NA |
NA |
NA |
300000 |
PubChem |
| ADORA3 |
1-Phenyl-3-pyridin-2-yl-isoquinoline |
12000000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |