| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| ADORA2B |
(2R,3R,4S,5R)-2-(6-amino-2-(2-(5-bromo-1H-indol-3-yl)ethoxy)-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol |
NA |
NA |
NA |
2741574 |
NA |
NA |
BindingDB |
| ADORA2B |
(2R,3R,4S,5R)-2-(6-amino-2-(2-(6-bromo-1H-indol-3-yl)ethoxy)-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol |
NA |
NA |
NA |
7816278 |
NA |
NA |
BindingDB |
| ADORA2B |
(2R,3R,4S,5R)-2-(6-amino-2-(2-(5-methoxy-1H-indol-3-yl)ethoxy)-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol |
NA |
NA |
NA |
799834 |
NA |
NA |
BindingDB |
| ADORA2B |
(2R,3R,4S,5R)-2-[6-(ethylamino)-2-[2-(1H-indol-3-yl)ethoxy]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol |
NA |
NA |
NA |
305492 |
NA |
NA |
BindingDB |
| ADORA2B |
(2S,3S,4R,5R)-5-(2-(2-(1H-indol-3-yl)ethoxy)-6-amino-9H-purin-9-yl)-N-ethyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide |
NA |
NA |
NA |
1011579 |
NA |
NA |
BindingDB |
| ADORA2B |
(2R,3R,4S,5R)-2-(2-(2-(1H-pyrrol-3-yl)ethoxy)-6-amino-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol |
NA |
NA |
NA |
387258 |
NA |
NA |
BindingDB |
| ADORA2B |
3-phenyl-N-propan-2-yl-1H-pyrazole-5-carboxamide |
NA |
NA |
196000 |
NA |
NA |
NA |
BindingDB|ChEMBL |
| ADORA2B |
Enprofylline |
130000 |
NA |
NA |
NA |
NA |
NA |
PubChem |
| ADORA2B |
2-(Benzylamino)pyrido[1,2-a]pyrimidin-4-one |
NA |
NA |
199000 |
NA |
NA |
NA |
BindingDB|ChEMBL |
| ADORA2B |
(2S,3S,4R,5R)-5-(6-amino-2-((S)-3-hydroxy-3-phenylprop-1-ynyl)-9H-purin-9-yl)-N-ethyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide |
NA |
NA |
NA |
4549881 |
NA |
NA |
BindingDB |
| ADORA2B |
(2S,3S,4R,5R)-5-[6-amino-2-[(3R)-3-hydroxy-3-phenylprop-1-ynyl]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide |
NA |
NA |
NA |
416869 |
NA |
NA |
BindingDB |
| ADORA2B |
3-Phenyl-[1,2,4]triazolo[4,3-b]pyridazin-6-amine |
NA |
NA |
120000 |
NA |
NA |
NA |
BindingDB |
| ADORA2B |
5-methyl-2-phenyl-2H-1,2,3-triazole-4-carboxamide |
NA |
NA |
140100 |
NA |
NA |
NA |
BindingDB|ChEMBL |
| ADORA2B |
N-quinolin-2-ylfuran-2-carboxamide |
NA |
NA |
123000 |
NA |
NA |
NA |
BindingDB|ChEMBL |
| ADORA2B |
2-(4-(2-Carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine |
NA |
NA |
NA |
213000|361000|6309573 |
NA |
NA |
BindingDB |
| ADORA2B |
3-Methyl-1,2,3,4-tetrahydroquinazoline-2,4-dione |
NA |
NA |
148000 |
NA |
NA |
NA |
BindingDB|ChEMBL |
| ADORA2B |
(2S,3S,4R,5R)-5-(6-amino-2-(hex-1-ynyl)-9H-purin-9-yl)-N-ethyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide |
NA |
NA |
NA |
164059 |
NA |
NA |
BindingDB |
| ADORA2B |
(2R,3R,4S,5R)-2-(6-amino-2-(2-(thiophen-2-yl)ethoxy)-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol |
NA |
NA |
NA |
562341 |
NA |
NA |
BindingDB |
| ADORA2B |
(2S,3S,4R,5R)-N-ethyl-3,4-dihydroxy-5-(6-(4-(2-oxo-2-(phenylamino)ethoxy)phenylamino)-9H-purin-9-yl)-tetrahydrofuran-2-carboxamide |
NA |
NA |
NA |
137088177 |
NA |
NA |
BindingDB |
| ADORA2B |
(2S,3S,4R,5R)-N-ethyl-5-(6-(4-(2-(4-fluorophenylamino)-2-oxoethoxy)phenylamino)-9H-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-carboxamide |
NA |
NA |
NA |
65765784 |
NA |
NA |
BindingDB |