| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| ADRA2A |
3-Benzyl-3-diethoxyphosphoryl-5-phenyl-3a,6a-dihydropyrrolo[3,4-c]pyrrole-4,6-dione |
114815.36 |
NA |
NA |
NA |
NA |
NA |
TTD |
| ADRA2A |
5-(2-Chloropyridin-3-yl)-3-diethoxyphosphoryl-3-phenyl-3a,6a-dihydropyrrolo[3,4-c]pyrrole-4,6-dione |
1000000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| ADRA2A |
3-Diethoxyphosphoryl-5-naphthalen-1-yl-3-phenyl-3a,6a-dihydropyrrolo[3,4-c]pyrrole-4,6-dione |
1000000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| ADRA2A |
5-(3-Chloro-4-fluorophenyl)-3-diethoxyphosphoryl-3-(4-methoxyphenyl)-3a,6a-dihydropyrrolo[3,4-c]pyrrole-4,6-dione |
1000000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| ADRA2A |
3-diethoxyphosphoryl-5-(2,3-dihydro-1H-inden-2-yl)-3-phenyl-3a,6a-dihydropyrrolo[3,4-c]pyrrole-4,6-dione |
363078.05 |
NA |
NA |
NA |
NA |
NA |
TTD |
| ADRA2A |
3-Diethoxyphosphoryl-3-(4-methoxyphenyl)-5-phenyl-3a,6a-dihydropyrrolo[3,4-c]pyrrole-4,6-dione |
141253.75 |
NA |
NA |
NA |
NA |
NA |
TTD |
| ADRA2A |
CR-4056 |
2238720|2238721.14 |
NA |
NA |
NA |
NA |
NA |
PubChem|TTD |
| ADRA2A |
Cefazolin |
NA |
NA |
NA |
NA |
NA |
300000 |
PubChem |
| ADRA2A |
Meropenem |
NA |
NA |
NA |
NA |
NA |
300000 |
PubChem |
| ADRA2A |
Cefepime |
NA |
NA |
NA |
NA |
NA |
300000 |
PubChem |
| ADRA2A |
Ceftazidime |
NA |
NA |
NA |
NA |
NA |
300000 |
PubChem |
| ADRA2A |
Aztreonam |
NA |
NA |
NA |
NA |
NA |
400000 |
PubChem |
| ADRA2A |
Carumonam |
NA |
NA |
NA |
NA |
NA |
500000 |
PubChem |
| ADRA2A |
Doripenem |
NA |
NA |
NA |
NA |
NA |
300000 |
PubChem |
| ADRA2A |
Yohimbine |
NA |
398000|195000|NA |
NA|5400000|150000 |
NA |
NA |
NA |
PubChem |
| ADRA2B |
Imipenem |
NA |
NA |
NA |
NA |
NA |
300000 |
PubChem |
| ADRA2B |
Cefazolin |
NA |
NA |
NA |
NA |
NA |
300000 |
PubChem |
| ADRA2B |
Meropenem |
NA |
NA |
NA |
NA |
NA |
300000 |
PubChem |
| ADRA2B |
Cefepime |
NA |
NA |
NA |
NA |
NA |
300000 |
PubChem |
| ADRA2B |
Ceftazidime |
NA |
NA |
NA |
NA |
NA |
300000 |
PubChem |