| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| ADRA1A |
disodium (R,R)-5-(2-((2-(3-chlorophenyl)-2-hydroxyethyl)-amino)propyl)-1,3-benzodioxole-2,3-dicarboxylate |
NA |
NA |
NA |
1000000 |
NA |
NA |
TTD |
| ADRA1A |
Cefepime |
NA |
NA |
NA |
NA |
NA |
300000 |
PubChem |
| ADRA1A |
Ceftazidime |
NA |
NA |
NA |
NA |
NA |
300000 |
PubChem |
| ADRA1A |
Aztreonam |
NA |
NA |
NA |
NA |
NA |
400000 |
PubChem |
| ADRA1A |
Carumonam |
NA |
NA |
NA |
NA |
NA |
500000 |
PubChem |
| ADRA1A |
Doripenem |
NA |
NA |
NA |
NA |
NA |
300000 |
PubChem |
| ADRA1B |
N-[(3aR,7aS)-3a,4,5,6,7,7a-hexahydro-1H-benzimidazol-2-yl]-5-bromoquinoxalin-6-amine |
104712.85 |
NA |
NA |
NA |
NA |
NA |
TTD |
| ADRA1B |
N-(5-bromoquinoxalin-6-yl)-4,5-dihydro-1,3-oxazol-2-amine |
141253.75 |
NA |
NA |
NA |
NA |
NA |
TTD |
| ADRA1B |
2-Fluoronorepinehprine |
134000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| ADRA1B |
Rilmenidine |
46773500000000 |
NA |
NA |
NA |
NA |
NA |
PubChem |
| ADRA1D |
(4R,5S)-4-(3,4-difluorophenyl)-N-[3-[4-(4-fluorophenyl)piperidin-1-yl]propyl]-5-methyl-2-oxo-1,3-oxazolidine-3-carboxamide |
253122 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ADRA1D |
N-(5-bromoquinoxalin-6-yl)-4,5-dihydro-1,3-oxazol-2-amine |
102329|102329.3 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ADRA2A |
1H-Imidazole, 4-(methoxy-1-naphthalenylmethyl)- |
NA |
379800 |
NA |
NA |
NA |
NA |
TTD |
| ADRA2A |
Imipenem |
NA |
NA |
NA |
NA |
NA |
300000 |
PubChem |
| ADRA2A |
(1H-Imidazol-4-yl)-naphthalen-1-yl-methanone; oxalic acid |
NA |
580400 |
NA |
NA |
NA |
NA |
TTD |
| ADRA2A |
1-(1-Naphthyl)-1-(1H-imidazol-4-yl)-2,2,2-trifluoroethanol |
NA |
300000 |
NA |
NA |
NA |
NA |
TTD |
| ADRA2A |
1-Benzyl-6-methyl-4-(3-methylbutylamino)pyridin-2-one |
110000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| ADRA2A |
1-Benzyl-6-methyl-4-(pentylamino)pyridin-2-one |
110000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| ADRA2A |
3-Diethoxyphosphoryl-3-phenyl-5-(2-phenylethyl)-3a,6a-dihydropyrrolo[3,4-c]pyrrole-4,6-dione |
169824.37 |
NA |
NA |
NA |
NA |
NA |
TTD |
| ADRA2A |
5-(3-Chloro-4-fluorophenyl)-3-diethoxyphosphoryl-3-(4-fluorophenyl)-3a,6a-dihydropyrrolo[3,4-c]pyrrole-4,6-dione |
416869.38 |
NA |
NA |
NA |
NA |
NA |
TTD |