| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| AHR |
2,8-Dichlorodibenzofuran |
NA |
NA |
NA |
257039.58 |
NA |
NA |
BindingDB|TTD |
| AHR |
Bisacodyl |
NA |
NA |
NA |
1000000 |
NA |
NA |
PubChem |
| AHR |
2-Chlorodibenzofuran |
NA |
NA |
NA |
279898.13 |
NA |
NA |
BindingDB|TTD |
| AHR |
2,3,4,5-Tetrachlorobiphenyl |
NA |
NA |
NA |
139958.73 |
NA |
NA |
BindingDB|TTD |
| AHR |
2,6-Dichlorodibenzofuran |
NA |
NA |
NA |
246036.76 |
NA |
NA |
BindingDB|TTD |
| AHR |
4-Chlorodibenzofuran |
NA |
NA |
NA |
1000000 |
NA |
NA |
BindingDB|TTD |
| AHR |
(E)-3,5,4'-Trimethoxystilbene |
130016958|130016957.8 |
NA |
NA |
NA |
NA|NA |
NA|NA |
BindingDB|TTD |
| AHR |
Dibenzofuran |
NA |
NA |
NA |
1000000 |
NA |
NA |
BindingDB|TTD |
| AHR |
Fluprednisolone |
NA |
NA |
NA |
NA |
105909 |
NA |
PubChem |
| AHR |
1,3-Dichloro-5-[(1E)-2-(4-chlorophenyl)ethenyl]-benzene |
831763771|833681185|831763771.1 |
NA |
NA |
NA |
NA|NA |
NA|NA |
BindingDB|TTD |
| AHR |
(Z)-3,5,4'-Trimethoxystilbene |
13335214 |
NA |
NA |
NA |
NA |
NA |
BindingDB |
| AK2 |
benzyl N-[5-[3-[5-[[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[[hydroxy-[hydroxy(phosphonooxy)phosphoryl]oxyphosphoryl]oxymethyl]oxolan-2-yl]purin-6-yl]amino]pentanoyl-methylamino]propyl-methylamino]-5-oxopentyl]carbamate |
6800000 |
NA |
NA |
NA |
NA |
NA |
BindingDB |
| AK2 |
benzyl N-[5-[[9-[(3R,4S,5R)-3,4-dihydroxy-5-[[hydroxy-[hydroxy(phosphonooxy)phosphoryl]oxyphosphoryl]oxymethyl]oxolan-2-yl]purin-6-yl]amino]pentyl]carbamate |
4700000 |
NA |
NA |
NA |
NA |
NA |
BindingDB |
| AK2 |
[[(2R,3S,4R)-5-[8-(6-acetamidohexylamino)-6-aminopurin-9-yl]-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate |
6700000 |
NA |
NA |
NA |
NA |
NA |
BindingDB |
| AK2 |
[[(2R,3S,4R)-5-[6-amino-8-(6-aminohexylamino)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate |
7300000 |
NA |
NA |
NA |
NA |
NA |
BindingDB |
| AK4 |
[[(2R,3S,4R,5R)-3,4-dihydroxy-5-[6-[5-[(2-iodoacetyl)amino]pentylamino]purin-9-yl]oxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate |
4800000 |
NA |
NA |
NA |
NA |
NA |
BindingDB |
| AKR1B1 |
(6R)-6-[(3S,5R,7S,10S,13R,14R,17R)-3,7-dihydroxy-4,4,10,13,14-pentamethyl-11,15-dioxo-2,3,5,6,7,12,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methyl-4-oxoheptanoic acid |
NA |
193500 |
NA |
NA |
NA |
NA |
TTD |
| AKR1B1 |
Enoxolone |
NA |
280000 |
NA |
NA |
NA |
NA |
PubChem|TTD |
| AKR1B1 |
Oleanolic Acid |
NA |
124000 |
NA |
NA |
NA |
NA |
PubChem|TTD |
| AKR1B1 |
(2R,3R,4S,5S,6R)-2-[[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-17-(2-hydroxy-6-methylhept-5-en-2-yl)-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |