| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| AKR1B1 |
(2S,3R,4S,5S,6R)-2-[(2R,3R,4S,5S,6R)-2-[[(3S,5R,6S,8R,9R,10R,12S,13R,14S,17S)-3,12-dihydroxy-17-[(2S)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-6-yl]oxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| AKR1B1 |
20(S)-Ginsenoside RH2 |
NA |
147300 |
NA |
NA |
NA |
NA |
TTD |
| AKR1B1 |
Ginsenoside Rh1 |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| AKR1B1 |
ethyl 2-[(4Z)-4-[[4-(2-ethoxy-2-oxoethoxy)phenyl]methylidene]-2-methyl-5-oxoimidazol-1-yl]acetate |
NA |
109000 |
NA |
NA |
NA |
NA |
TTD |
| AKR1B1 |
2-(15-Hydroxy-2-oxo-6-tricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaenyl)acetic acid |
NA |
280000 |
NA |
NA |
NA |
NA |
TTD |
| AKR1B1 |
Midkine (Human) |
NA |
160000 |
NA |
NA |
NA |
NA |
TTD |
| AKR1B1 |
(4-Hydroxy-5-oxo-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-2-yl)-acetic acid |
NA |
110000 |
NA |
NA |
NA |
NA |
TTD |
| AKR1B1 |
Ganoderic Acid D |
NA |
195300 |
NA |
NA |
NA |
NA |
TTD |
| AKR1B1 |
ethyl 2-[(4Z)-4-benzylidene-2-methyl-5-oxoimidazol-1-yl]acetate |
NA |
112000 |
NA |
NA |
NA |
NA |
TTD |
| AKR1B1 |
Ganoderenic Acid A |
NA |
119200 |
NA |
NA |
NA |
NA |
TTD |
| AKR1B1 |
(4-Hydroxy-6-methoxy-2-methyl-chroman-4-yl)-acetic acid |
NA |
281000 |
NA |
NA |
NA |
NA |
TTD |
| AKR1B1 |
4-Chlorophenylacetic acid |
170000 |
NA |
NA |
NA |
NA |
NA |
BindingDB |
| AKR1B1 |
CID 20055989 |
NA |
174700 |
NA |
NA |
NA |
NA |
TTD |
| AKR1B1 |
Ganoderic Acid J |
NA |
194400 |
NA |
NA |
NA |
NA |
TTD |
| AKR1B1 |
Ganolucidic acid B |
NA |
199200 |
NA |
NA |
NA |
NA |
TTD |
| AKR1B1 |
Methyl Ganoderate A |
NA |
189400 |
NA |
NA |
NA |
NA |
TTD |
| AKR1B1 |
Coumarin |
NA |
500000 |
NA |
NA |
NA |
NA |
PubChem|TTD |
| AKR1B1 |
Sorbinil |
NA |
2200000|1400000 |
NA |
NA |
NA |
NA |
PubChem |
| AKR1B1 |
Salicylic Acid |
NA |
1000000 |
NA |
NA |
NA |
NA |
PubChem|TTD |
| AKR1B1 |
Ketoprofen |
NA |
180000 |
NA |
NA |
NA |
NA |
PubChem|TTD |