| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| AKR1B1 |
(S)-Mandelic acid |
621000 |
NA |
NA |
NA |
NA |
NA |
PubChem |
| AKR1B1 |
Cinnamic Acid |
1390000|280000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|PubChem |
| AKR1B1 |
(20R)-Ginsenoside Rg3 |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| AKR1B1 |
Ganoderic acid A |
NA |
193500 |
NA |
NA |
NA |
NA |
TTD |
| AKR1B1 |
Ganoderic Acid C1 |
NA |
194400 |
NA |
NA |
NA |
NA |
TTD |
| AKR1B1 |
Biochanin A |
NA |
127000 |
NA |
NA |
NA |
NA |
TTD |
| AKR1B1 |
Vitexin |
NA |
566660 |
NA |
NA |
NA |
NA |
TTD |
| AKR1B1 |
Rutin |
NA |
294500 |
NA |
NA |
NA |
NA |
PubChem |
| AKR1B1 |
Daidzein |
NA |
161800 |
NA |
NA |
NA |
NA |
PubChem|TTD |
| AKR1B1 |
20(R)-Ginsenoside |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| AKR1B1 |
4-Hydroxycoumarins |
NA |
400000 |
NA |
NA |
NA |
NA |
TTD |
| AKR1B1 |
methyl (6R)-6-[(5R,7S,10S,11S,13R,14R,17R)-7,11-dihydroxy-4,4,10,13,14-pentamethyl-3,15-dioxo-2,5,6,7,11,12,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methyl-4-oxoheptanoate |
NA |
189400 |
NA |
NA |
NA |
NA |
TTD |
| AKR1B1 |
Methyl Ganoderenate A |
NA |
183900 |
NA |
NA |
NA |
NA |
TTD |
| AKR1B1 |
methyl (2R,6R)-2-methyl-4-oxo-6-[(3S,5R,7S,10S,13R,14R,15S,17R)-3,7,15-trihydroxy-4,4,10,13,14-pentamethyl-11-oxo-1,2,3,5,6,7,12,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]heptanoate |
NA |
183900 |
NA |
NA |
NA |
NA |
TTD |
| AKR1B1 |
Ganoderic Acid K |
NA |
174200 |
NA |
NA |
NA |
NA |
TTD |
| AKR1B1 |
Ginsenoside K |
NA |
200000 |
NA |
NA |
NA |
NA |
PubChem|TTD |
| AKR1B1 |
Ginsenoside Rg3 |
NA |
200000 |
NA |
NA |
NA |
NA |
PubChem|TTD |
| AKR1B1 |
6-hydroxy-2H-chromen-2-one |
NA |
171000 |
NA |
NA |
NA |
NA |
TTD |
| AKR1B1 |
Phenylacetic Acid |
303000|360000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|PubChem |
| AKR1B10 |
Luteolin |
NA |
107800 |
NA |
NA |
NA |
NA |
PubChem |