| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| F10 |
[2-[(2-benzyl-3-ethoxycarbonyl-6-methoxy-1-benzofuran-5-yl)oxymethyl]-3-ethoxycarbonyl-1H-indol-5-yl] sulfate |
NA |
195000 |
NA |
NA |
NA |
NA |
BindingDB |
| F10 |
[3-ethoxycarbonyl-2-[(3-ethoxycarbonyl-2-methyl-1H-indol-5-yl)oxymethyl]-1-[(2-methylpropan-2-yl)oxycarbonyl]indol-5-yl] sulfate |
NA |
229000 |
NA |
NA |
NA |
NA |
BindingDB |
| F10 |
[3-ethoxycarbonyl-2-[[3-ethoxycarbonyl-2-[(3-ethoxycarbonyl-6-methoxy-2-methyl-1-benzofuran-5-yl)oxymethyl]-6-methoxy-1-benzofuran-5-yl]oxymethyl]-1H-indol-5-yl] sulfate |
NA |
344000 |
NA |
NA |
NA |
NA |
BindingDB |
| F10 |
Pentasodium;[4-[3-[8-[4-[[2-(3,4-disulfonatooxyphenyl)-4-oxo-3,7-disulfonatooxychromen-5-yl]oxymethyl]triazol-1-yl]octyl]-4-oxoquinazolin-2-yl]phenyl] sulfate |
NA |
250000 |
NA |
NA |
NA |
NA |
TTD |
| F10 |
N-[(6-amino-2-methylpyridin-3-yl)methyl]-1-[[4-(pyrazol-1-ylmethyl)phenyl]methyl]pyrazole-4-carboxamide |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| F10 |
(12E)-20-amino-22-methyl-6-(pyrazol-1-ylmethyl)-9,17-dioxa-1,21,25,29-tetrazatetracyclo[25.2.1.03,8.018,23]triaconta-3(8),4,6,12,18,20,22,27(30),28-nonaen-26-one |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| F10 |
ASGPR modulator-1 |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| F10 |
20-Amino-22-methyl-6-(pyrazol-1-ylmethyl)-9,17-dioxa-1,21,25,29-tetrazatetracyclo[25.2.1.03,8.018,23]triaconta-3(8),4,6,13,18,20,22,27(30),28-nonaen-26-one |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| F10 |
(8e)-3-Amino-1-Methyl-15-[(1h-Pyrazol-1-Yl)methyl]-7,10,11,12,24,25-Hexahydro-6h,18h,23h-19,22-(Metheno)pyrido[4,3-J][1,9,13,17,18]benzodioxatriazacyclohenicosin-23-One |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| F10 |
2-[3-(1H-1,3-benzodiazol-2-yl)-4-hydroxy-5-(3-nitrophenyl)phenyl]acetic acid |
150000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| F10 |
2-(3-{5-amino-1H-imidazo[4,5-b]pyridin-2-yl}-4-hydroxy-5-(3-nitrophenyl)phenyl)acetic acid |
150000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| F10 |
6-Fluoro-2-[2-hydroxy-3-(piperidin-3-ylmethoxy)-phenyl]-1H-benzoimidazole-5-carboxamidine |
125000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| F10 |
6-Fluoro-2-[2-hydroxy-3-(pyrrolidin-2-ylmethoxy)-phenyl]-1H-benzoimidazole-5-carboxamidine |
167000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| F10 |
2-(3,4-Dihydroxyphenyl)-5-[[4-[[2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-4-oxochromen-5-yl]oxymethyl]phenyl]methoxy]-3,7-dihydroxychromen-4-one |
NA |
212000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| F10 |
1-benzoyl-6-methoxy-3-[4-(2-oxopiperidin-1-yl)phenyl]-2H-quinazolin-4-one |
NA |
546000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| F10 |
1-(3-chlorobenzoyl)-6-methoxy-3-[4-(2-oxopiperidin-1-yl)phenyl]-2H-quinazolin-4-one |
NA |
243000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| F10 |
6-methoxy-1-(3-methoxybenzoyl)-3-[4-(2-oxopiperidin-1-yl)phenyl]-2H-quinazolin-4-one |
NA |
354000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| F10 |
Octasodium;[2-(3,4-disulfonatooxyphenyl)-5-[[4-[[2-(3,4-disulfonatooxyphenyl)-4-oxo-3,7-disulfonatooxychromen-5-yl]oxymethyl]phenyl]methoxy]-4-oxo-3-sulfonatooxychromen-7-yl] sulfate |
NA |
505000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| F10 |
6-methoxy-1-(4-methoxybenzoyl)-3-[4-(2-oxopiperidin-1-yl)phenyl]-2H-quinazolin-4-one |
NA |
113000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| F10 |
1-(5-chlorothiophene-2-carbonyl)-6-methoxy-3-[4-(2-oxopiperidin-1-yl)phenyl]-2H-quinazolin-4-one |
NA |
179000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |