| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| MAPK9 |
4-bromo-2-(2,6-dichlorophenyl)-5-(2,4,6-trifluorobenzyloxy)pyridazin-3(2H)-one |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| MAPK9 |
4-bromo-2-(2,6-dichlorophenyl)-5-(2,3,4-trifluorobenzyloxy)pyridazin-3(2H)-one |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| MAPK9 |
4-bromo-5-(4-chloro-2-fluorobenzyloxy)-2-(2,6-dichlorophenyl)pyridazin-3(2H)-one |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| MAPK9 |
4-bromo-5-(2,4-difluorobenzyloxy)-2-(2,6-difluorophenyl)pyridazin-3(2H)-one |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| MAPK9 |
3-(5-bromo-4-(2,4-difluorobenzyloxy)-6-oxopyridazin-1(6H)-yl)-N,4-dimethylbenzamide |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| MAPK9 |
3-[4-[(2,4-difluorophenyl)methoxy]-5-methyl-6-oxopyrimidin-1-yl]-N-(2-hydroxyethyl)-4-methylbenzamide |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| MAPK9 |
4-bromo-2-(2,6-dichlorophenyl)-5-(4-fluorobenzyloxy)pyridazin-3(2H)-one |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| MAPKAPK2 |
2,4-Diamino-5H-thiochromeno[2,3-b]pyridine-3-carbonitrile |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| MAPKAPK2 |
4-(4-Benzylphenylamino)-6-(2-morpholinoethylamino)-1,7-naphthyridine-3-carbonitrile |
NA |
400000 |
NA |
NA |
NA |
NA |
TTD |
| MAPKAPK2 |
(1E,4S,4aR,5R,6aS,7S,9aR)-5-(acetyloxy)-1-[[[3-(dimethylamino)propyl]methylamino]methylene]-4a,5,6,6a,7,8,9,9a-octahydro-cyclopenta[5,6]naphtho[1,2-c]pyran-2,10(1H,4H)-dione |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| MAPKAPK2 |
1,3-bis(ethylamino)-6,7-dihydroxy-9H-xanthene-2-carbonitrile |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| MAPKAPK2 |
1,3-diamino-6-methoxy-9-phenyl-9H-xanthene-2-carbonitrile |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| MAPKAPK2 |
1,3-diamino-6-hydroxy-9-phenyl-9H-xanthene-2-carbonitrile |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| MAPKAPK2 |
6-(2-Morpholinoethylamino)-4-(4-(phenylthio)phenylamino)-1,7-naphthyridine-3-carbonitrile |
NA |
400000 |
NA |
NA |
NA |
NA |
TTD |
| MAPKAPK2 |
6-methoxy-2,3,4,9-tetrahydro-1H-carbazole-1-carboxylic acid |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| MAPKAPK2 |
[(1S,3aR,6E,9S,9aR,10R,11aS)-6-[[tert-butyl(2-hydroxyethyl)amino]methylidene]-1,5-dihydroxy-9-(methoxymethyl)-9a,11a-dimethyl-4,7-dioxo-2,3,3a,9,10,11-hexahydro-1H-indeno[4,5-h]isochromen-10-yl] acetate |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| MAPKAPK2 |
2-(6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)acetic acid |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| MAPKAPK2 |
4-(3-Chloro-4-fluoro-phenylamino)-6-(2-morpholin-4-yl-ethylamino)-1,7-naphthyridine-3-carbonitrile |
NA |
400000 |
NA |
NA |
NA |
NA |
TTD |
| MAPKAPK2 |
8-chloro-4-[(3-chloro-4-fluorophenyl)amino]-6-({[1-(1-propylpiperidin-4-yl)-1H-1,2,3-triazol-4-yl]methyl}amino)quinoline-3-carbonitrile |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| MAPKAPK2 |
Substituted 6-aminoquinoline-3-carbonitrile, 36 |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |