| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| ACHE |
|
NA |
870000 |
NA |
NA |
NA |
NA |
BindingDB |
| ACHE |
N,N'-(biphenyl-4,4'-diyl)bis(N-(phenylsulfonyl)acetamide) (3a) |
NA |
103210 |
NA |
NA |
NA |
NA |
BindingDB |
| ACHE |
N,N'-(3,3'-dimethylbiphenyl-4,4'-diyl)bis(N-isopropylbenzenesulfonamide) (3j) |
NA |
101210 |
NA |
NA |
NA |
NA |
BindingDB |
| ACHE |
methyl 5-(dimethylcarbamoyloxy)-1-methyl-4H-quinoline-3-carboxylate |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| ACHE |
7-Hydroxy-6-(2-(R)-Hydroxy-3-Methylbut-3-Enyl)Coumarin |
NA |
130000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
6H-Cyclohepta[b]quinolin-11-amine, 1-chloro-7,8,9,10-tetrahydro- |
NA |
223000 |
NA |
NA |
NA |
NA |
BindingDB |
| ACHE |
ethyl (2S,6R)-4-(4-methoxyanilino)-1-(4-methoxyphenyl)-2,6-bis(4-methylphenyl)-3,6-dihydro-2H-pyridine-5-carboxylate |
NA |
4980000 |
NA |
NA |
NA |
NA |
BindingDB |
| ACHE |
methyl (2S,6R)-4-(4-fluoroanilino)-1-(4-fluorophenyl)-2,6-diphenyl-3,6-dihydro-2H-pyridine-5-carboxylate |
NA |
15100000|15120000 |
NA |
NA |
NA |
NA |
BindingDB |
| ACHE |
ethyl (2S,6R)-2,6-bis(4-chlorophenyl)-4-(4-fluoroanilino)-1-(4-fluorophenyl)-3,6-dihydro-2H-pyridine-5-carboxylate |
NA |
550000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
methyl (2S,6R)-4-(4-fluoroanilino)-1,2,6-tris(4-fluorophenyl)-3,6-dihydro-2H-pyridine-5-carboxylate |
NA |
3200000 |
NA |
NA |
NA |
NA |
BindingDB |
| ACHE |
methyl (2S,6R)-4-(4-bromoanilino)-1-(4-bromophenyl)-2,6-bis(4-chlorophenyl)-3,6-dihydro-2H-pyridine-5-carboxylate |
NA |
880000 |
NA |
NA |
NA |
NA |
BindingDB |
| ACHE |
methyl (2S,6R)-4-(4-bromoanilino)-1-(4-bromophenyl)-2,6-bis(4-methoxyphenyl)-3,6-dihydro-2H-pyridine-5-carboxylate |
NA |
2160000 |
NA |
NA |
NA |
NA |
BindingDB |
| ACHE |
methyl (2S,6R)-4-anilino-2,6-bis(1,3-benzodioxol-5-yl)-1-phenyl-3,6-dihydro-2H-pyridine-5-carboxylate |
NA |
3270000 |
NA |
NA |
NA |
NA |
BindingDB |
| ACHE |
2-[3-[(E)-hydroxyiminomethyl]pyridin-1-ium-1-yl]-N-(1,3-thiazol-2-yl)acetamide |
NA |
NA |
115000 |
NA |
NA |
NA |
BindingDB |
| ACHE |
2-[3-[(E)-hydroxyiminomethyl]pyridin-1-ium-1-yl]-N-(4-phenyl-1,3-thiazol-2-yl)acetamide |
NA |
NA |
350600|682700|762600 |
NA |
NA |
NA |
BindingDB |
| ACHE |
2-[3-[(E)-hydroxyiminomethyl]pyridin-1-ium-1-yl]-N-[4-(4-methylphenyl)-1,3-thiazol-2-yl]acetamide |
NA |
NA |
145600 |
NA |
NA |
NA |
BindingDB |
| ACHE |
2-[3-[(E)-hydroxyiminomethyl]pyridin-1-ium-1-yl]-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]acetamide |
NA |
NA |
113800|641000 |
NA |
NA |
NA |
BindingDB |
| ACHE |
ethyl 2-[2-[[2-[3-[(E)-hydroxyiminomethyl]pyridin-1-ium-1-yl]acetyl]amino]-1,3-thiazol-4-yl]acetate |
NA |
NA |
104500|109200 |
NA |
NA |
NA |
BindingDB |
| ACHE |
|
NA |
2360000 |
NA |
NA |
NA |
NA |
BindingDB |
| ACHE |
|
NA |
990000 |
NA |
NA |
NA |
NA |
BindingDB |