| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| ACHE |
4-Amino-2-(piperidin-1-ylmethyl)phenol dihydrochloride |
NA |
456000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
4-Amino-2-(morpholin-4-ylmethyl)phenol;dihydrochloride |
NA |
270600 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
5-Methoxy-2-[4-(4-methylpiperazin-1-yl)phenyl]-1H-benzo[d] imidazole (3e) |
NA |
229300 |
NA |
NA |
NA |
NA |
BindingDB |
| ACHE |
5-Methoxy-2-[4-(4-ethylpiperazin-1-yl)phenyl]-1H-benzo[d]imidazole (3f) |
NA |
120600 |
NA |
NA |
NA |
NA |
BindingDB |
| ACHE |
5-Methoxy-2-[4-(4-benzylpiperazin-1-yl)phenyl]-1H-benzo[d]imidazole (3h) |
NA |
144300 |
NA |
NA |
NA |
NA |
BindingDB |
| ACHE |
1,3-Dimethyl-2-pyridin-4-yl-2,4-dihydroquinazolin-6-ol |
NA |
242400 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
1,3-dimethyl-2-(1H-pyrrol-3-yl)-2,4-dihydroquinazolin-6-ol |
NA |
115900 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
2-(2-Methoxyphenyl)-1,3-dimethyl-2,4-dihydroquinazolin-6-ol |
NA |
192800 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
1,3-Dimethyl-2-thiophen-2-yl-2,4-dihydroquinazolin-6-ol |
NA |
225800 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
2-(Furan-3-yl)-1,3-dimethyl-2,4-dihydroquinazolin-6-ol |
NA |
341700 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
1,3-Dimethyl-2-naphthalen-1-yl-2,4-dihydroquinazolin-6-ol |
NA |
341700 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
1-Methyl-2-phenyl-3-propan-2-yl-2,4-dihydroquinazolin-6-ol |
NA |
253000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
1-Methyl-2-phenyl-3-propyl-2,4-dihydroquinazolin-6-ol |
NA |
279300 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
1,3-Dimethyl-2-phenyl-2,4-dihydroquinazolin-6-ol |
NA |
327000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
2-(4-Chlorophenyl)-1,3-dimethyl-2,4-dihydroquinazolin-6-ol |
NA |
235600 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
2-(3-Chlorophenyl)-1,3-dimethyl-2,4-dihydroquinazolin-6-ol |
NA |
242400 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
2-(4-Fluorophenyl)-1,3-dimethyl-2,4-dihydroquinazolin-6-ol |
NA |
143400 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
1,3-Dimethyl-2-(4-methylphenyl)-2,4-dihydroquinazolin-6-ol |
NA |
109900 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
1,3-Dimethyl-2-(3-methylphenyl)-2,4-dihydroquinazolin-6-ol |
NA |
437000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
1,3-Dimethyl-2-(2-methylphenyl)-2,4-dihydroquinazolin-6-ol |
NA |
143400 |
NA |
NA |
NA |
NA |
BindingDB|TTD |