| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| ACHE |
2-(4-Methoxyphenyl)-1,3-dimethyl-2,4-dihydroquinazolin-6-ol |
NA |
103800 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
2-(Dimethylamino)propyl 4-[[4-[4-[2-(dimethylamino)propoxycarbonyl]phenoxy]-6-methoxy-1,3,5-triazin-2-yl]oxy]benzoate |
NA |
110500 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
(3,7,8-trimethyl-1,5-dihydro-[1,3]dioxepino[5,6-c]pyridin-7-ium-9-yl) N,N-dimethylcarbamate;bromide |
NA |
150000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
[4-[4-[(2-oxochromen-7-yl)oxymethyl]triazol-1-yl]phenyl] N-heptylcarbamate |
NA |
157500 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
(7,8-dimethyl-1,5-dihydro-[1,3]dioxepino[5,6-c]pyridin-7-ium-9-yl) N,N-dimethylcarbamate;bromide |
NA |
130000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
(3,3,7,8-tetramethyl-1,5-dihydro-[1,3]dioxepino[5,6-c]pyridin-7-ium-9-yl) N,N-dimethylcarbamate;bromide |
NA |
500000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
(3-ethyl-7,8-dimethyl-1,5-dihydro-[1,3]dioxepino[5,6-c]pyridin-7-ium-9-yl) N,N-dimethylcarbamate;bromide |
NA |
280000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
(7,8-dimethyl-3-propyl-1,5-dihydro-[1,3]dioxepino[5,6-c]pyridin-7-ium-9-yl) N,N-dimethylcarbamate;bromide |
NA |
140000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
(3-tert-butyl-7,8-dimethyl-1,5-dihydro-[1,3]dioxepino[5,6-c]pyridin-7-ium-9-yl) N,N-dimethylcarbamate;bromide |
NA |
110000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
1-[2-[3-[[(2Z)-2-hydroxyiminoacetyl]amino]pyridin-1-ium-1-yl]ethyl]pyridin-1-ium-4-carboxamide;dibromide |
NA |
NA|1870000 |
167000|NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
(7,8-dimethyl-3-propan-2-yl-1,5-dihydro-[1,3]dioxepino[5,6-c]pyridin-7-ium-9-yl) N,N-dimethylcarbamate;bromide |
NA |
260000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
1-[3-[3-[[(2Z)-2-hydroxyiminoacetyl]amino]pyridin-1-ium-1-yl]propyl]pyridin-1-ium-4-carboxamide;dibromide |
NA |
1670000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
1-[4-[3-[[(2Z)-2-hydroxyiminoacetyl]amino]pyridin-1-ium-1-yl]butyl]pyridin-1-ium-4-carboxamide;dibromide |
NA |
1560000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
1-[5-[3-[[(2Z)-2-hydroxyiminoacetyl]amino]pyridin-1-ium-1-yl]pentyl]pyridin-1-ium-4-carboxamide;dibromide |
NA |
770000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
(2E)-6-methoxy-2-[[1-[(3-methoxyphenyl)methyl]piperidin-4-yl]methylidene]-3H-inden-1-one |
119490 |
NA |
NA |
NA |
NA |
NA |
BindingDB |
| ACHE |
N-Cyclopentyliminobis(methylenephosphonic acid) (9) |
NA |
11070000 |
NA |
NA |
NA |
NA |
BindingDB |
| ACHE |
but-(2E)-en-1,4-diyl-1,1'-bis(4-ethylpyridinium) dibromide (6) |
NA |
212000 |
NA |
NA |
NA |
NA |
BindingDB |
| ACHE |
but-(2E)-en-1,4-diyl-1,1'-bis(4-hydroxypyridinium) dibromide (12) |
NA |
509000 |
NA |
NA |
NA |
NA |
BindingDB |
| ACHE |
but-(2E)-en-1,4-diyl-1,1'-bis(4-hydroxymethylpyridinium) dibromide (13) |
NA |
799000 |
NA |
NA |
NA |
NA |
BindingDB |
| ACHE |
but-(2E)-en-1,4-diyl-1,1'-bis(4-methylcarbonylpyridinium) dibromide (17) |
NA |
139000 |
NA |
NA |
NA |
NA |
BindingDB |