| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| ACHE |
1-[4-[4-[(E)-hydroxyiminomethyl]pyridin-1-ium-1-yl]butyl]pyridin-1-ium-4-carboxamide;dibromide |
110000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| ACHE |
N'-[2-(diethylamino)ethyl]-N-hydroxy-3-phenyl-1,2,4-oxadiazole-5-carboximidamide |
NA |
260000 |
NA |
NA |
NA |
NA |
TTD |
| ACHE |
2-[(E)-hydroxyiminomethyl]-6-[5-(1,2,3,4-tetrahydroacridin-9-ylsulfanyl)pentyl]pyridin-3-ol |
NA |
307000 |
NA |
NA |
NA |
NA |
TTD |
| ACHE |
(E)-N-(1-benzylpiperidin-4-yl)-3-hydroxy-2-nitrosobut-2-enamide |
233800 |
NA |
NA |
NA |
NA |
NA |
TTD |
| ACHE |
(E)-N-[(1-benzylpiperidin-4-yl)methyl]-3-hydroxy-2-nitrosobut-2-enamide |
2303000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| ACHE |
(E)-N-[[1-[(3,4-dimethoxyphenyl)methyl]piperidin-4-yl]methyl]-3-hydroxy-2-nitrosobut-2-enamide |
1625000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| ACHE |
(E)-N-[3-(6,7-dimethoxy-1-phenyl-3,4-dihydro-1H-isoquinolin-2-yl)propyl]-3-hydroxy-2-nitrosobut-2-enamide |
1926000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| ACHE |
(E)-N-[3-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)propyl]-3-hydroxy-2-nitrosobut-2-enamide |
2671000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| ACHE |
(NE)-N-[[1-[5-(6,7-dimethoxy-1-phenyl-3,4-dihydro-1H-isoquinolin-2-yl)pentyl]imidazol-2-yl]methylidene]hydroxylamine |
NA |
930000 |
NA |
NA |
NA |
NA |
TTD |
| ACHE |
(NE)-N-[[1-[6-(6,7-dimethoxy-1-phenyl-3,4-dihydro-1H-isoquinolin-2-yl)hexyl]imidazol-2-yl]methylidene]hydroxylamine |
NA |
870000 |
NA |
NA |
NA |
NA |
TTD |
| ACHE |
4-[3-[(1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3H-2-benzofuran-5-yl]-1H-1,2,4-triazol-5-yl]phenol |
NA |
387560 |
NA |
NA |
NA |
NA |
TTD |
| ACHE |
1-[(E)-(6-hydroxy-4-oxo-2-sulfanylidene-1H-pyrimidin-5-yl)methylideneamino]-3-(4-methoxyphenyl)thiourea |
NA |
206000|206310 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
1-(4-chlorophenyl)-3-[(E)-(6-hydroxy-4-oxo-2-sulfanylidene-1H-pyrimidin-5-yl)methylideneamino]thiourea |
NA |
121000|121110 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
1-[(E)-(6-hydroxy-4-oxo-2-sulfanylidene-1H-pyrimidin-5-yl)methylideneamino]-3-phenylthiourea |
NA |
115000|115110 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
[(E)-(6-hydroxy-2,4-dioxo-1H-pyrimidin-5-yl)methylideneamino]thiourea |
NA |
119000|119110 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
2-[4-[(E)-hydroxyiminomethyl]pyridin-1-ium-1-yl]-N-(1,3-thiazol-2-yl)acetamide;chloride |
NA |
2360000 |
NA |
NA |
NA |
NA |
TTD |
| ACHE |
2-[4-[(E)-hydroxyiminomethyl]pyridin-1-ium-1-yl]-N-(4-phenyl-1,3-thiazol-2-yl)acetamide;chloride |
NA |
990000 |
NA |
NA |
NA |
NA |
TTD |
| ACHE |
2-[4-[(E)-hydroxyiminomethyl]pyridin-1-ium-1-yl]-N-[4-(4-methylphenyl)-1,3-thiazol-2-yl]acetamide;chloride |
NA |
970000 |
NA |
NA |
NA |
NA |
TTD |
| ACHE |
2-[4-[(E)-hydroxyiminomethyl]pyridin-1-ium-1-yl]-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]acetamide;iodide |
NA |
1660000 |
NA |
NA |
NA |
NA |
TTD |
| ACHE |
ethyl 2-[2-[[2-[4-[(E)-hydroxyiminomethyl]pyridin-1-ium-1-yl]acetyl]amino]-1,3-thiazol-4-yl]acetate;chloride |
NA |
2270000 |
NA |
NA |
NA |
NA |
TTD |