| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| ACHE |
4-[4-[[2-hydroxy-3-[(E)-hydroxyiminomethyl]-5-methylphenyl]methylamino]phenyl]morpholin-3-one |
NA |
5305000 |
NA |
NA |
NA |
NA |
BindingDB |
| ACHE |
6-chloro-3-[1-[[2-hydroxy-3-[(E)-hydroxyiminomethyl]-5-methylphenyl]methyl]piperidin-4-yl]-1H-benzimidazol-2-one |
NA |
1905000 |
NA |
NA |
NA |
NA |
BindingDB |
| ACHE |
4-chloro-2-[[4-[[2-(1-hydroxycyclohexyl)-2-(4-methoxyphenyl)ethyl]-methylamino]anilino]methyl]-6-[(E)-hydroxyiminomethyl]phenol |
NA |
2505000 |
NA |
NA |
NA |
NA |
BindingDB |
| ACHE |
2-[(3-fluoro-4-morpholin-4-ylanilino)methyl]-6-[(E)-hydroxyiminomethyl]-4-methylphenol |
NA |
3269000 |
NA |
NA |
NA |
NA |
BindingDB |
| ACHE |
4-[[5-chloro-2-hydroxy-3-[(E)-hydroxyiminomethyl]phenyl]methylamino]-N-(1,3-thiazol-2-yl)benzenesulfonamide |
NA |
4275000 |
NA |
NA |
NA |
NA |
BindingDB |
| ACHE |
2-[(E)-hydroxyiminomethyl]-4-methyl-6-[(4-pyrazol-1-ylanilino)methyl]phenol |
NA |
3183000 |
NA |
NA |
NA |
NA |
BindingDB |
| ACHE |
2-(2-Aminoethyl)-7-methoxy-2-methyl-3,4-dihydrochromen-6-ol |
NA |
101000 |
NA |
NA |
NA |
NA |
BindingDB |
| ACHE |
(12R)-7,16-dimethoxy-3,5-dioxa-11-azapentacyclo[10.7.1.02,6.08,20.014,19]icosa-1,6,8(20),14(19),15,17-hexaen-18-ol |
NA |
161900 |
NA |
NA |
NA |
NA |
BindingDB |
| ACHE |
1,1''-Bis(pyridinium)-1,2-phenyldimethylene dibromide |
NA |
636000 |
NA |
NA |
NA |
NA |
BindingDB |
| ACHE |
2-[4-[4-[1-[3-(1,3-dioxoisoindol-2-yl)propyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]butyl]triazol-1-yl]-N-[2-(5-methoxy-1H-indol-2-yl)ethyl]acetamide |
NA |
173900 |
NA |
NA |
NA |
NA |
BindingDB |
| ACHE |
2-(cyclopropanecarbonylamino)-N-[5-[[1-[(3-methylphenyl)methyl]piperidin-4-yl]methylcarbamoyl]pyridin-3-yl]pyridine-4-carboxamide |
NA |
6364000 |
NA |
NA |
NA |
NA |
BindingDB |
| ACHE |
4-[4-[4-[1-[3-(1,3-dioxoisoindol-2-yl)propyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]butyl]triazol-1-yl]-N-[2-(5-methoxy-1H-indol-2-yl)ethyl]butanamide |
NA |
158600 |
NA |
NA |
NA |
NA |
BindingDB |
| ACHE |
(2R,3R,4S,5S,6R)-2-[4-[1-[3-[5-hydroxy-6-[(E)-hydroxyiminomethyl]pyridin-2-yl]propyl]triazol-4-yl]butoxy]-6-(hydroxymethyl)oxane-3,4,5-triol |
NA |
1600000 |
NA |
NA |
NA |
NA |
BindingDB |
| ACHE |
(2R,3R,4S,5S,6R)-2-[3-[5-hydroxy-6-[(E)-hydroxyiminomethyl]pyridin-2-yl]propoxy]-6-(hydroxymethyl)oxane-3,4,5-triol |
NA |
140000 |
NA |
NA |
NA |
NA |
BindingDB |
| ACHE |
(2R,3R,4S,5S,6R)-2-[4-[1-[4-[5-hydroxy-6-[(E)-hydroxyiminomethyl]pyridin-2-yl]butyl]triazol-4-yl]butoxy]-6-(hydroxymethyl)oxane-3,4,5-triol |
NA |
580000 |
NA |
NA |
NA |
NA |
BindingDB |
| ACHE |
1-[3-(3,4-Dimethoxyphenyl)-5-(4-phenylphenyl)-3,4-dihydropyrazol-2-yl]ethanone |
NA |
1420000 |
NA |
NA |
NA |
NA |
BindingDB |
| ACHE |
4-[2-Acetyl-5-(4-phenylphenyl)-3,4-dihydropyrazol-3-yl]benzoic acid |
NA |
1540000 |
NA |
NA |
NA |
NA |
BindingDB |
| ACHE |
(1aS,2S,3S,7bS)-2-hydroxy-3-methoxy-6-[2-(4-methoxyphenyl)ethyl]-1a,2,3,7b-tetrahydrooxireno[2,3-h]chromen-4-one |
NA |
155600 |
NA |
NA |
NA |
NA |
BindingDB |
| ACHE |
1-[3-Phenyl-5-(4-phenylphenyl)-3,4-dihydropyrazol-2-yl]ethanone |
NA |
1320000 |
NA |
NA |
NA |
NA |
BindingDB |
| ACHE |
1-[3-(3-Nitrophenyl)-5-(4-phenylphenyl)-3,4-dihydropyrazol-2-yl]ethanone |
NA |
1020000 |
NA |
NA |
NA |
NA |
BindingDB |