| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| ACHE |
2-(3,4-Dimethoxyphenyl)-2-(4-methylpiperazin-1-yl)acetonitrile |
NA |
379000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
2-(1,3-Benzodioxol-5-yl)-2-(4-methylpiperazin-1-yl)acetonitrile |
NA |
275300 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
2-Pyrrolidin-1-yl-2-(3,4,5-trimethoxyphenyl)acetonitrile |
NA |
321000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
2-Piperidin-1-yl-2-(3,4,5-trimethoxyphenyl)acetonitrile |
NA |
381000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
|
110000 |
NA |
NA |
NA |
NA |
NA |
BindingDB |
| ACHE |
(2-{4-[7-(Benzylmethylamino)heptyloxy]phenyl}benzofuran-3-yl)-m-tolylmethanone |
NA |
127000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
(2-{4-[7-(Benzylmethylamino)heptyloxy]phenyl}benzofuran-3-yl)-(3-methoxyphenyl)-methanone |
NA |
127000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
(2-{4-[7-(Benzylmethylamino)heptyloxy]phenyl}benzofuran-3-yl)-(4-methoxyphenyl)-methanone |
NA |
281000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
(2-{4-[7-(Benzylmethylamino)heptyloxy]phenyl}benzofuran-3-yl)-(3,4-dimethoxyphenyl)-methanone |
NA |
177000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
3-(1-Acetylpiperidin-4-yl)-1-[4-(trifluoromethoxy)phenyl]urea |
NA |
115000 |
NA |
NA |
NA |
NA |
BindingDB |
| ACHE |
Isosorbide-2-(benzylcarbamate)-5-benzoate |
NA |
221000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
methyl (2S,6R)-4-anilino-2,6-bis(4-chlorophenyl)-1-phenyl-3,6-dihydro-2H-pyridine-5-carboxylate |
NA |
880000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
methyl (2S,6R)-4-(4-bromoanilino)-1-(4-bromophenyl)-2,6-bis(4-methylphenyl)-3,6-dihydro-2H-pyridine-5-carboxylate |
NA |
2480000 |
NA |
NA |
NA |
NA |
BindingDB |
| ACHE |
ethyl (2S,6R)-4-anilino-1,2,6-triphenyl-3,6-dihydro-2H-pyridine-5-carboxylate |
NA |
2950000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
tert-butyl (2S,6R)-4-anilino-1,2,6-triphenyl-3,6-dihydro-2H-pyridine-5-carboxylate |
NA |
2790000 |
NA |
NA |
NA |
NA |
BindingDB |
| ACHE |
methyl (2S,6R)-4-anilino-2,6-bis(3-nitrophenyl)-1-phenyl-3,6-dihydro-2H-pyridine-5-carboxylate |
NA |
510000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| ACHE |
ethyl (2S,6R)-4-anilino-2,6-bis(4-methylphenyl)-1-phenyl-3,6-dihydro-2H-pyridine-5-carboxylate |
NA |
5580000 |
NA |
NA |
NA |
NA |
BindingDB |
| ACHE |
methyl (2S,6R)-4-anilino-2,6-bis(4-methylphenyl)-1-phenyl-3,6-dihydro-2H-pyridine-5-carboxylate |
NA |
5730000 |
NA |
NA |
NA |
NA |
BindingDB |
| ACHE |
(3S,5aR)-3-methoxy-1-methyl-3-oxo-4,5,5a,6-tetrahydrofuro[3,4-e]oxaphosphepin-8-one |
140000 |
NA |
NA |
NA |
NA |
NA |
BindingDB |
| ACHE |
(4S)-1-(3,5-dibromophenyl)-N-[(2S,3R)-4-[[3-(dimethylamino)phenyl]methylamino]-3-hydroxy-1-phenylbutan-2-yl]-2-oxoimidazolidine-4-carboxamide |
NA |
NA|560000 |
140000|NA |
NA |
NA |
NA |
BindingDB |