| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| SLC6A9 |
2,4-dichloro-N-[[1-(1-methylimidazol-4-yl)sulfonylpiperidin-4-yl]-thiophen-2-ylmethyl]benzamide |
NA |
374000 |
NA |
NA |
NA |
NA |
TTD |
| SLC6A9 |
2,4-dichloro-N-[[1-(4-propylsulfonylpiperazin-1-yl)-2,3-dihydroinden-1-yl]methyl]benzamide |
NA |
6400000 |
NA |
NA |
NA |
NA |
TTD |
| SLC6A9 |
Glycine |
NA |
NA|106000 |
NA |
106000|NA |
NA |
NA |
PubChem |
| SLC6A9 |
3-fluoro-N-[2-(1-methylimidazol-4-yl)sulfonyl-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-4-yl]benzamide |
NA |
10000000 |
NA |
NA |
NA |
NA |
TTD |
| SLC6A9 |
N-[[(1S,5R)-3-(1-methylimidazol-4-yl)sulfonyl-6-pyridin-2-yl-3-azabicyclo[3.1.0]hexan-6-yl]methyl]-2-(trifluoromethyl)benzamide |
NA |
185000 |
NA |
NA |
NA |
NA |
TTD |
| SLC6A9 |
2,4-dichloro-N-[[(1R,5S)-3-(1-methylimidazol-4-yl)sulfonyl-6-pyridin-2-yl-3-azabicyclo[3.1.0]hexan-6-yl]methyl]benzamide |
NA |
247000 |
NA |
NA |
NA |
NA |
TTD |
| SLC7A11 |
Methyl 2-hydroxy-5-[[4-[(2-pyridinylamino)sulfonyl]phenyl]ethynyl]benzoate |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| SLC7A11 |
methyl 2-hydroxy-5-[(E)-2-[4-(pyridin-2-ylsulfamoyl)phenyl]ethenyl]benzoate |
NA |
900000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SLC7A11 |
2-Hydroxy-5-[2-[4-[(2-pyridinylamino)sulfonyl]phenyl]ethyl]benzoic acid |
NA |
700000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SLC7A11 |
3-Phenylethynyl-benzoic acid |
NA |
270000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SLC7A11 |
Mesalamine |
NA |
1000000 |
NA |
NA |
NA |
NA |
PubChem|TTD |
| SLC7A11 |
2-Hydroxy-5-(phenylethynyl)benzoic acid |
NA |
150000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SLC7A11 |
4-[(2S)-2-amino-2-carboxyethyl]-5-(2-naphthalen-1-ylethyl)-1,2-oxazole-3-carboxylic acid |
117000 |
NA |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SLC7A11 |
Sulfapyridine |
NA |
1000000 |
NA |
NA |
NA |
NA |
PubChem|TTD |
| SLC7A11 |
Sulfasalazine |
NA |
450000|460000 |
NA |
NA |
NA |
NA |
PubChem |
| SLC7A11 |
|
NA |
450000|460000 |
NA |
NA |
NA |
NA |
BindingDB |
| SLC7A11 |
|
NA |
200000 |
NA |
NA |
NA |
NA |
BindingDB |
| SLC7A11 |
3-[2-[4-(Pyridin-2-ylsulfamoyl)phenyl]ethyl]benzoic acid |
NA |
920000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SLC7A11 |
Methyl 2-hydroxy-5-[2-[4-(pyridin-2-ylsulfamoyl)phenyl]ethyl]benzoate |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| SLC7A11 |
Cysteine |
NA |
116000 |
NA |
NA |
NA |
NA |
BindingDB|PubChem |