| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| SLC6A4 |
2-[2-[2-[[3-(2-aminoethyl)-1H-indol-5-yl]oxy]ethoxy]ethoxy]ethanethiol |
NA |
115000 |
NA |
NA |
NA |
NA |
BindingDB |
| SLC6A5 |
Glycine |
NA |
128000|NA |
NA |
NA|128000 |
NA |
NA |
PubChem |
| SLC6A6 |
Gamma-Aminobutyric Acid |
NA |
354000|NA |
NA |
NA|354000 |
NA |
NA |
PubChem |
| SLC6A9 |
7-benzyl-1H,2H,3H,4H,5H,6H,7H,8H-pyrido[3,4-d]pyrimidine-2,4-dione |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| SLC6A9 |
5-((8-Hydroxy-9H-purin-6-YL)thio)pentanoic acid |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| SLC6A9 |
Hinokinin |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| SLC6A9 |
4-chloro-N-[2-(1-methylimidazol-4-yl)sulfonyl-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-4-yl]benzamide |
NA |
1029000 |
NA |
NA |
NA |
NA |
TTD |
| SLC6A9 |
2-chloro-N-[2-(1-methylimidazol-4-yl)sulfonyl-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-4-yl]benzamide |
NA |
115000 |
NA |
NA |
NA |
NA |
TTD |
| SLC6A9 |
N-[2-(1-methylimidazol-4-yl)sulfonyl-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-4-yl]-2-(trifluoromethyl)benzamide |
NA |
112000 |
NA |
NA |
NA |
NA |
TTD |
| SLC6A9 |
2,4-difluoro-N-[2-(1-methylimidazol-4-yl)sulfonyl-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-4-yl]benzamide |
NA |
926000 |
NA |
NA |
NA |
NA |
TTD |
| SLC6A9 |
2-fluoro-N-[2-(1-methylimidazol-4-yl)sulfonyl-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-4-yl]benzamide |
NA |
1815000 |
NA |
NA |
NA |
NA |
TTD |
| SLC6A9 |
3,4-dichloro-N-[2-(1-methylimidazol-4-yl)sulfonyl-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-4-yl]benzamide |
NA |
891000 |
NA |
NA |
NA |
NA |
TTD |
| SLC6A9 |
4-fluoro-N-[2-(1-methylimidazol-4-yl)sulfonyl-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-4-yl]benzamide |
NA |
2215000 |
NA |
NA |
NA |
NA |
TTD |
| SLC6A9 |
2,6-difluoro-N-[2-(1-methylimidazol-4-yl)sulfonyl-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-4-yl]benzamide |
NA |
631000 |
NA |
NA |
NA |
NA |
TTD |
| SLC6A9 |
3,4-difluoro-N-[2-(1-methylimidazol-4-yl)sulfonyl-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-4-yl]benzamide |
NA |
1569000 |
NA |
NA |
NA |
NA |
TTD |
| SLC6A9 |
N-[2-(1-methylimidazol-4-yl)sulfonyl-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-4-yl]cyclohexanecarboxamide |
NA |
617000 |
NA |
NA |
NA |
NA |
TTD |
| SLC6A9 |
3-[(2,8-dihydroxy-9H-purin-6-yl)thio]propanoic acid |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| SLC6A9 |
2,4-dichloro-N-(phenyl(1-(propylsulfonyl)azetidin-3-yl)methyl)benzamide |
NA |
627000 |
NA |
NA |
NA |
NA |
TTD |
| SLC6A9 |
2,4-Dichloro-N-[phenyl[1-(propylsulfonyl)-4-piperidinyl]methyl]benzamide |
NA |
1500000 |
NA |
NA |
NA |
NA |
TTD |
| SLC6A9 |
2,4-dichloro-N-[[1-(1-methylimidazol-4-yl)sulfonylpiperidin-4-yl]-phenylmethyl]benzamide |
NA |
201000 |
NA |
NA |
NA |
NA |
TTD |