| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| SYK |
US10842803, Structure TABLE 1.97 |
NA |
569460 |
NA |
NA |
NA |
NA |
BindingDB |
| SYK |
6-(1H-indazol-6-yl)-8-(5-morpholinopyridin-2-ylamino)imidazo[1,2-a]pyridine-5-carboxylic acid |
NA |
4227200 |
NA |
NA |
NA |
NA |
BindingDB |
| SYK |
|
NA |
168000 |
NA |
NA |
NA |
NA |
BindingDB |
| SYK |
6-(2-Phenyl-ethenesulfonylamino)-hexanoic acid |
NA |
8000000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SYK |
Cyclohexanemalonic acid |
NA |
5900000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SYK |
(S)-4-{(S)-2-[(S)-2-Acetylamino-3-(4-phosphonooxy-phenyl)-propionylamino]-4-carboxy-butyrylamino}-4-((1S,2S)-1-carbamoyl-2-methyl-butylcarbamoyl)-butyric acid |
NA |
171000 |
NA |
NA |
NA |
NA |
TTD |
| SYK |
[5-[[(1S)-1-[3-[(3,4-dichlorophenyl)methyl]-1,2,4-oxadiazol-5-yl]ethyl]carbamoylamino]naphthalen-2-yl] dihydrogen phosphate |
NA |
310000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SYK |
Ac-Tyr(PO3H2)-Asn-Glu-Leu-NH2 |
NA |
420000 |
NA |
NA |
NA |
NA |
TTD |
| SYK |
[4-[(2S)-2-acetamido-3-[[(1S)-4-amino-4-oxo-1-[3-[(4,6,6-trimethylcyclohexa-2,4-dien-1-yl)methyl]-1,2,4-oxadiazol-5-yl]butyl]amino]-3-oxopropyl]phenyl] dihydrogen phosphate |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| SYK |
Ac-Tyr(PO3H2)-Asp-Val-Leu-NH2 |
NA |
389000 |
NA |
NA |
NA |
NA |
TTD |
| SYK |
2-Cyclooct-4-enyl-malonic acid |
NA |
7700000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SYK |
4-[(2S)-2-{[(1S)-3-carbamoyl-1-{3-[(4-methylphenyl)methyl]-1,2,4-oxadiazol-5-yl}propyl]carbamoyl}-2-acetamidoethyl]phenoxyphosphonic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| SYK |
4-[(2S)-2-{[(1S)-3-carbamoyl-1-(3-{[4-(propan-2-yl)phenyl]methyl}-1,2,4-oxadiazol-5-yl)propyl]carbamoyl}-2-acetamidoethyl]phenoxyphosphonic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| SYK |
4-[(2S)-2-{[(1S)-3-carbamoyl-1-{3-[(4-chlorophenyl)methyl]-1,2,4-oxadiazol-5-yl}propyl]carbamoyl}-2-acetamidoethyl]phenoxyphosphonic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| SYK |
4-[(2S)-2-{[(1S)-3-carbamoyl-1-{3-[(3-chlorophenyl)methyl]-1,2,4-oxadiazol-5-yl}propyl]carbamoyl}-2-acetamidoethyl]phenoxyphosphonic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| SYK |
4-[(2S)-2-{[(1S)-3-carbamoyl-1-{3-[(2,4-dichlorophenyl)methyl]-1,2,4-oxadiazol-5-yl}propyl]carbamoyl}-2-acetamidoethyl]phenoxyphosphonic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| SYK |
4-[(2S)-2-{[(1S)-3-carbamoyl-1-[3-(naphthalen-1-ylmethyl)-1,2,4-oxadiazol-5-yl]propyl]carbamoyl}-2-acetamidoethyl]phenoxyphosphonic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| SYK |
4-[(2S)-2-{[(1S)-3-carbamoyl-1-[3-(2-phenylethyl)-1,2,4-oxadiazol-5-yl]propyl]carbamoyl}-2-acetamidoethyl]phenoxyphosphonic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| SYK |
4-[(2S)-2-acetamido-2-{[(1S)-1-(3-{[3-(trifluoromethyl)phenyl]methyl}-1,2,4-oxadiazol-5-yl)ethyl]carbamoyl}ethyl]phenoxyphosphonic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| SYK |
4-[(2S)-2-{[(1S)-1-{3-[(3,4-dibromophenyl)methyl]-1,2,4-oxadiazol-5-yl}ethyl]carbamoyl}-2-acetamidoethyl]phenoxyphosphonic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |