| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| STS |
Sulfamic acid 4-iodophenyl ester |
NA |
560000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| STS |
(8R,9S,13S,14S)-3-hydroxy-13-methyl-17-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-2,4-dicarbaldehyde |
NA |
224000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| STS |
(8R,9S,13S,14S)-2-bromo-3-hydroxy-13-methyl-17-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-4-carbaldehyde |
NA |
145000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| STS |
[4-[2-[2-[2-(2-Azaniumylethoxy)ethoxy]ethylamino]-1-fluoro-2-oxoethyl]phenyl] sulfate |
NA |
15000000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| STS |
[(8S,9S,13S,14S)-17-formyl-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl]methanesulfonic acid |
140000 |
NA |
NA |
NA |
NA |
NA |
BindingDB |
| STS |
Sulfamic acid 4-{(Z)-1-[4-(2-dimethylamino-ethoxy)-phenyl]-2-phenyl-but-1-enyl}-phenyl ester |
500000 |
NA |
NA |
NA |
NA |
NA |
TTD |
| SUCNR1 |
Methylmalonic Acid |
NA |
NA |
NA |
169000|284000 |
NA |
NA |
GtoPDB |
| SUV39H1 |
DC_05 |
NA |
150000 |
NA |
NA |
NA |
NA |
TTD |
| SYK |
N-{1-[3-(3,4-Dichloro-benzyl)-[1,2,4]oxadiazol-5-yl]-2-hydroxy-ethyl}-3-(4-phosphonooxy-benzyl)-succinamic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| SYK |
(6aR,10aS)-4-Methoxy-7,9-dimethyl-4,6,6a,7,8,10a-hexahydro-indolo[4,3-fg]quinoline |
NA |
285000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SYK |
[2-[[(1S)-1-[3-[(3,4-dichlorophenyl)methyl]-1,2,4-oxadiazol-5-yl]ethyl]carbamoyl]-1H-indol-5-yl] dihydrogen phosphate |
NA |
434000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SYK |
N-{1-[3-(3,4-Dichloro-benzyl)-[1,2,4]oxadiazol-5-yl]-ethyl}-3-(4-phosphonooxy-benzyl)-succinamic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| SYK |
2-(4-{4-[2-(5-Carboxy-pentylsulfamoyl)-vinyl]-phenylcarbamoyl}-cyclohexyl)-malonic acid |
NA |
350000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SYK |
4-N-cyclohexyl-2-N-(2-methoxy-4-morpholin-4-ylphenyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine |
NA |
154000|153000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SYK |
[4-[3-[[(1S)-1-[3-[(3,4-dichlorophenyl)methyl]-1,2,4-oxadiazol-5-yl]ethyl]amino]-3-oxopropyl]phenyl] dihydrogen phosphate |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| SYK |
[4-[(2S)-2-(tert-butylsulfonylmethyl)-3-oxo-3-[[(1S)-1-[3-[[4-(trifluoromethyl)phenyl]methyl]-1,2,4-oxadiazol-5-yl]ethyl]amino]propyl]phenyl] dihydrogen phosphate |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| SYK |
{4-Amino-2-[(4-ethoxyphenyl)amino]-1,3-thiazol-5-yl}(3-methoxyphenyl)methanone |
NA |
200000 |
NA |
NA |
NA |
NA |
TTD |
| SYK |
(3Z)-1-(2-chlorobenzyl)-3-(5-oxo-2-thioxoimidazolidin-4-ylidene)-1,3-dihydro-2H-indol-2-one |
NA |
168000 |
NA |
NA |
NA |
NA |
TTD |
| SYK |
US10842803, Structure TABLE 1.76 |
NA |
128000 |
NA |
NA |
NA |
NA |
BindingDB |
| SYK |
US10842803, Structure TABLE 1.79 |
NA |
252000 |
NA |
NA |
NA |
NA |
BindingDB |