| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| SYK |
4-[(2S)-2-{[(1S)-1-{3-[(3-bromo-4-chlorophenyl)methyl]-1,2,4-oxadiazol-5-yl}ethyl]carbamoyl}-2-acetamidoethyl]phenoxyphosphonic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| SYK |
4-[(2S)-2-{[(1S)-1-{3-[(3-chloro-4-iodophenyl)methyl]-1,2,4-oxadiazol-5-yl}ethyl]carbamoyl}-2-acetamidoethyl]phenoxyphosphonic acid |
NA |
464000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SYK |
4-[(2S)-2-{[(1S)-1-{3-[(3-bromo-4-iodophenyl)methyl]-1,2,4-oxadiazol-5-yl}ethyl]carbamoyl}-2-acetamidoethyl]phenoxyphosphonic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| SYK |
4-[(2S)-2-acetamido-2-{[2-(3-{[4-(trifluoromethyl)phenyl]methyl}-1,2,4-oxadiazol-5-yl)propan-2-yl]carbamoyl}ethyl]phenoxyphosphonic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| SYK |
4-[(2S)-2-acetamido-2-{[(3-{[4-(trifluoromethyl)phenyl]methyl}-1,2,4-oxadiazol-5-yl)methyl]carbamoyl}ethyl]phenoxyphosphonic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| SYK |
4-[(2S)-2-acetamido-2-{[2-(3-{[4-(trifluoromethyl)phenyl]methyl}-1,2,4-oxadiazol-5-yl)ethyl]carbamoyl}ethyl]phenoxyphosphonic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| SYK |
4-[(2S)-2-{[(1S)-2-carbamoyl-1-(3-{[4-(trifluoromethyl)phenyl]methyl}-1,2,4-oxadiazol-5-yl)ethyl]carbamoyl}-2-acetamidoethyl]phenoxyphosphonic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| SYK |
4-[(2S)-2-acetamido-2-{[(1S)-2-(1H-indol-3-yl)-1-(3-{[4-(trifluoromethyl)phenyl]methyl}-1,2,4-oxadiazol-5-yl)ethyl]carbamoyl}ethyl]phenoxyphosphonic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| SYK |
4-[(2S)-2-acetamido-2-{[(1S)-1-(3-{[4-(trifluoromethyl)phenyl]methyl}-1,2,4-oxadiazol-5-yl)propyl]carbamoyl}ethyl]phenoxyphosphonic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| SYK |
4-[(2S)-2-{[(1S)-1-{3-[(4-chlorophenyl)methyl]-1,2,4-oxadiazol-5-yl}-2-hydroxyethyl]carbamoyl}-2-acetamidoethyl]phenoxyphosphonic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| SYK |
4-[(2S)-2-acetamido-2-{[(1S)-1-{3-[(4-fluorophenyl)methyl]-1,2,4-oxadiazol-5-yl}-2-hydroxyethyl]carbamoyl}ethyl]phenoxyphosphonic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| SYK |
4-[(2S)-2-{[(1S)-1-{3-[(4-bromophenyl)methyl]-1,2,4-oxadiazol-5-yl}-2-hydroxyethyl]carbamoyl}-2-acetamidoethyl]phenoxyphosphonic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| SYK |
4-[(2S)-2-acetamido-2-{[(1S)-2-hydroxy-1-{3-[(4-iodophenyl)methyl]-1,2,4-oxadiazol-5-yl}ethyl]carbamoyl}ethyl]phenoxyphosphonic acid |
NA |
452000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SYK |
4-[(2S)-2-[1-(thiophen-2-yl)acetamido]-2-{[(1S)-1-(3-{[4-(trifluoromethyl)phenyl]methyl}-1,2,4-oxadiazol-5-yl)ethyl]carbamoyl}ethyl]phenoxyphosphonic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| SYK |
4-[(2S)-2-[1-(naphthalen-2-yl)acetamido]-2-{[(1S)-1-(3-{[4-(trifluoromethyl)phenyl]methyl}-1,2,4-oxadiazol-5-yl)ethyl]carbamoyl}ethyl]phenoxyphosphonic acid |
NA |
302000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SYK |
4-[(2S)-2-{[(1S)-1-(3-benzyl-1,2,4-oxadiazol-5-yl)-3-carbamoylpropyl]carbamoyl}-2-acetamidoethyl]phenoxyphosphonic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| SYK |
4-[(2S)-2-{[(1S)-3-carbamoyl-1-{3-[(3,4-dichlorophenyl)methyl]-1,2,4-oxadiazol-5-yl}propyl]carbamoyl}-2-acetamidoethyl]phenoxyphosphonic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| SYK |
4-[(2S)-2-{[(1S)-3-carbamoyl-1-[3-(naphthalen-2-ylmethyl)-1,2,4-oxadiazol-5-yl]propyl]carbamoyl}-2-acetamidoethyl]phenoxyphosphonic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| SYK |
4-[(2S)-2-{[(1S)-1-{3-[(3,4-dichlorophenyl)methyl]-1,2,4-oxadiazol-5-yl}ethyl]carbamoyl}-2-acetamidoethyl]phenoxyphosphonic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| SYK |
4-[(2S)-2-acetamido-2-{[(1S)-1-[3-(naphthalen-2-ylmethyl)-1,2,4-oxadiazol-5-yl]ethyl]carbamoyl}ethyl]phenoxyphosphonic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |