| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| SYK |
US10842803, Structure TABLE 1.81 |
NA |
532000 |
NA |
NA |
NA |
NA |
BindingDB |
| SYK |
US10842803, Structure TABLE 1.82 |
NA |
320000 |
NA |
NA |
NA |
NA |
BindingDB |
| SYK |
US10842803, Structure TABLE 1.83 |
NA |
271000 |
NA |
NA |
NA |
NA |
BindingDB |
| SYK |
US10842803, Structure TABLE 1.86 |
NA |
215000 |
NA |
NA |
NA |
NA |
BindingDB |
| SYK |
US10842803, Structure TABLE 1.87 |
NA |
278000 |
NA |
NA |
NA |
NA |
BindingDB |
| SYK |
2-(6-(5-chloro-8-(5-(4-isopropylpiperazin-1-yl)pyridin-2-ylamino)imidazo[1,2-a]pyridin-6-yl)-1-methyl-1H-indol-3-yl)ethanol |
NA |
218000 |
NA |
NA |
NA |
NA |
BindingDB |
| SYK |
US10842803, Structure TABLE 1.1 |
NA |
1049100 |
NA |
NA |
NA |
NA |
BindingDB |
| SYK |
N-[6-(1H-indazol-6-yl)imidazo[1,2-a]pyridin-8-yl]pyrimidin-4-amine |
NA |
297200 |
NA |
NA |
NA |
NA |
BindingDB |
| SYK |
US10842803, Structure TABLE 1.9 |
NA |
548100 |
NA |
NA |
NA |
NA |
BindingDB |
| SYK |
Ac-pTyr-Glu-Thr-Leu-NH(2) |
NA |
NA|570000 |
166000|NA |
NA |
NA |
NA |
BindingDB|TTD |
| SYK |
US10842803, Structure TABLE 1.72 |
NA |
301000 |
NA |
NA |
NA |
NA |
BindingDB |
| SYK |
(4R)-4-[(1R)-1-(1,6-naphthyridin-5-yloxy)ethyl]pyrrolidin-2-one |
NA |
2156000 |
NA |
NA |
NA |
NA |
BindingDB |
| SYK |
4-[(2S)-2-acetamido-2-{[(1S)-1-{3-[(4-methylphenyl)methyl]-1,2,4-oxadiazol-5-yl}ethyl]carbamoyl}ethyl]phenoxyphosphonic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| SYK |
4-[(2S)-2-{[(1S)-1-{3-[(4-chlorophenyl)methyl]-1,2,4-oxadiazol-5-yl}ethyl]carbamoyl}-2-acetamidoethyl]phenoxyphosphonic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| SYK |
4-[(2S)-2-acetamido-2-{[(1S)-1-{3-[(4-fluorophenyl)methyl]-1,2,4-oxadiazol-5-yl}ethyl]carbamoyl}ethyl]phenoxyphosphonic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| SYK |
4-[(2S)-2-{[(1S)-1-{3-[(4-bromophenyl)methyl]-1,2,4-oxadiazol-5-yl}ethyl]carbamoyl}-2-acetamidoethyl]phenoxyphosphonic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| SYK |
4-[(2S)-2-{[(1S)-1-{3-[(3-chlorophenyl)methyl]-1,2,4-oxadiazol-5-yl}ethyl]carbamoyl}-2-acetamidoethyl]phenoxyphosphonic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| SYK |
4-[(2S)-2-acetamido-2-{[(1S)-1-{3-[(4-iodophenyl)methyl]-1,2,4-oxadiazol-5-yl}ethyl]carbamoyl}ethyl]phenoxyphosphonic acid |
NA |
472000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SYK |
4-[(2S)-2-(1-phenylacetamido)-2-{[(1S)-1-(3-{[4-(trifluoromethyl)phenyl]methyl}-1,2,4-oxadiazol-5-yl)ethyl]carbamoyl}ethyl]phenoxyphosphonic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| SYK |
4-[(2S)-2-[1-(3,4-difluorophenyl)acetamido]-2-{[(1S)-1-(3-{[4-(trifluoromethyl)phenyl]methyl}-1,2,4-oxadiazol-5-yl)ethyl]carbamoyl}ethyl]phenoxyphosphonic acid |
NA |
397000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |